Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.58 |
| ▸ | MMP8 | P22894 | 1/20 | 0.58 |
| ▸ | FNTA | P49354 | 15/20 | 0.53 |
| ▸ | FNTB | P49356 | 15/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7078041 | 0.91 | RORC (0.47) | MMP2MMP8DHODH | |
| SCHEMBL7130423 | 0.88 | RORC (0.44) | MMP2MMP8FNTAFNTBDHODH | |
| SCHEMBL8360105 | 0.87 | RORC (0.43) | MMP2MMP8FNTAFNTBCA12 | |
| SCHEMBL7077549 | 0.82 | DHODH (0.44) | MMP2MMP8CA12CA1CA2 | |
| SCHEMBL7078388 | 0.82 | NAMPT (0.44) | CA12CA1CA2CA9 | |
| SCHEMBL7080988 | 0.81 | ITGB3 (0.44) | CA12CA1CA2CA9 | |
| SCHEMBL7078046 | 0.80 | DHODH (0.42) | MMP2MMP8CA12CA1CA2 | |
| SCHEMBL7077873 | 0.79 | FNTA (0.43) | FNTAFNTBMTNR1B | |
| SCHEMBL7189858 | 0.78 | FNTA (0.50) | FNTAFNTB | |
| SCHEMBL7073837 | 0.77 | FNTA (0.52) | MMP2MMP8FNTAFNTBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |