Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 3/20 | 0.50 |
| ▸ | BCR | P11274 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | FABP6 | P51161 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074772 | 0.84 | MGLL (0.66) | MGLLMAPK1HDAC4HDAC2HDAC8 | |
| SCHEMBL7384950 | 0.80 | FABP6 (0.46) | MGLLMAPK1FABP6 | |
| SCHEMBL7076687 | 0.80 | TSHR (0.59) | MGLLHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL13838154 | 0.80 | ALDH1A1 (0.53) | MGLLMAPK1ABL1BCRPKM | |
| SCHEMBL7071414 | 0.79 | FASN (0.60) | MGLLHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL7075196 | 0.79 | MGLL (0.54) | MGLLMAPK1HDAC4HDAC2HDAC8 | |
| SCHEMBL9763711 | 0.78 | PKM (0.74) | MAPK1TDP1PKMFABP6POLB | |
| SCHEMBL7074230 | 0.78 | HPGD (0.53) | MGLLPKMHDAC4HDAC2HDAC8 | |
| SCHEMBL7071696 | 0.77 | ALDH1A1 (0.61) | MGLLHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL7649408 | 0.77 | DGAT1 (0.58) | MGLLHDAC4POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |