Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PLG | P00747 | 10/20 | 0.52 |
| ▸ | F10 | P00742 | 6/20 | 0.51 |
| ▸ | PLAU | P00749 | 6/20 | 0.51 |
| ▸ | ST14 | Q9Y5Y6 | 6/20 | 0.51 |
| ▸ | F2 | P00734 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7071442 | 0.89 | SMN1; SMN2 (0.56) | ALDH1A1GAAPLGLMNAPKM | |
| SCHEMBL7074309 | 0.87 | PKM (0.63) | ALDH1A1GAAPLGF10F2 | |
| SCHEMBL7077118 | 0.87 | ALDH1A1 (0.52) | ALDH1A1GAAPLGLMNAPKM | |
| SCHEMBL7073640 | 0.87 | PLG (0.56) | ALDH1A1GAAPLGF10PLAU | |
| SCHEMBL7074609 | 0.86 | PLG (0.66) | ALDH1A1GAAPLGF10PLAU | |
| SCHEMBL7074612 | 0.83 | PLG (0.56) | ALDH1A1GAAPLGF10PLAU | |
| SCHEMBL7071685 | 0.81 | KMT2A (0.49) | ALDH1A1GAAPLGF10PLAU | |
| SCHEMBL7074560 | 0.78 | PLG (0.57) | ALDH1A1PLGF10PLAUST14 | |
| SCHEMBL7075075 | 0.77 | CNR1 (0.56) | ALDH1A1GAAPLGF2LMNA | |
| SCHEMBL7076655 | 0.77 | ALDH1A1 (0.55) | ALDH1A1GAATSHRPLGF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |