Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 12/20 | 0.66 |
| ▸ | PKM | P14618 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | F10 | P00742 | 4/20 | 0.57 |
| ▸ | PLAU | P00749 | 3/20 | 0.56 |
| ▸ | F2 | P00734 | 2/20 | 0.56 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.56 |
| ▸ | F12 | P00748 | 1/20 | 0.56 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.56 |
| ▸ | PROC | P04070 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074612 | 0.92 | PLG (0.56) | PLGPKMALDH1A1LMNAGAA | |
| SCHEMBL7073594 | 0.90 | PKM (0.72) | PLGPKMALDH1A1LMNAGAA | |
| SCHEMBL7073640 | 0.87 | PLG (0.56) | PLGPKMALDH1A1LMNAGAA | |
| SCHEMBL7071442 | 0.86 | SMN1; SMN2 (0.56) | PLGPKMALDH1A1LMNAGAA | |
| SCHEMBL7074294 | 0.86 | ALDH1A1 (0.54) | PLGPKMALDH1A1LMNAGAA | |
| SCHEMBL7077118 | 0.86 | ALDH1A1 (0.52) | PLGPKMALDH1A1LMNAGAA | |
| SCHEMBL7074309 | 0.86 | PKM (0.63) | PLGPKMALDH1A1LMNAGAA | |
| SCHEMBL9951915 | 0.86 | PKM (0.80) | PKMALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL7074277 | 0.83 | F10 (0.67) | PLGPKMALDH1A1LMNAGAA | |
| SCHEMBL7074428 | 0.82 | PKM (0.62) | PLGPKMALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |
| EP-1025086-A1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GmbH (DE) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999016751-A1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 1999-04-08 | — | — | WO | disclosed |