Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 14/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 8/20 | 0.44 |
| ▸ | F2 | P00734 | 7/20 | 0.44 |
| ▸ | PLAU | P00749 | 7/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7072198 | 0.88 | F2 (0.53) | PLGPOLBF2ALDH1A1GLA | |
| SCHEMBL7071685 | 0.79 | KMT2A (0.49) | PLGPOLBF10F2PLAU | |
| SCHEMBL7071442 | 0.78 | SMN1; SMN2 (0.56) | PLGALDH1A1 | |
| SCHEMBL7074294 | 0.78 | ALDH1A1 (0.54) | PLGF10F2PLAUST14 | |
| SCHEMBL7074309 | 0.78 | PKM (0.63) | PLGF10F2ALDH1A1 | |
| SCHEMBL7077118 | 0.78 | ALDH1A1 (0.52) | PLGPOLBALDH1A1 | |
| SCHEMBL7073640 | 0.77 | PLG (0.56) | PLGPOLBF10F2PLAU | |
| SCHEMBL7074609 | 0.77 | PLG (0.66) | PLGF10F2PLAUST14 | |
| SCHEMBL7075829 | 0.75 | F2 (0.49) | PLGF2ALDH1A1GLA | |
| SCHEMBL7074612 | 0.74 | PLG (0.56) | PLGF10F2PLAUST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |