Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3113134 | 0.83 | MAPT (0.45) | ALDH1A1MAPTUSP2CYP3A4SMN1; SMN2 | |
| SCHEMBL3123704 | 0.81 | MAPT (0.48) | ALDH1A1MAPTUSP2CYP3A4SMN1; SMN2 | |
| SCHEMBL6067595 | 0.81 | L3MBTL1 (0.47) | ALDH1A1MAPTUSP2CYP3A4SMN1; SMN2 | |
| SCHEMBL9331429 | 0.81 | FAAH (0.53) | MAPTUSP2CYP3A4LMNARECQL | |
| SCHEMBL28046958 | 0.80 | CA1 (0.44) | MAPTCPB2 | |
| SCHEMBL7074449 | 0.79 | MAPT (0.49) | ALDH1A1MAPTUSP2CYP3A4SMN1; SMN2 | |
| SCHEMBL9453302 | 0.79 | MAPT (0.49) | ALDH1A1MAPTUSP2CYP3A4SMN1; SMN2 | |
| SCHEMBL7224713 | 0.79 | MAPT (0.49) | ALDH1A1MAPTUSP2CYP3A4SMN1; SMN2 | |
| SCHEMBL7510923 | 0.79 | ZDHHC7 (0.46) | MAPTCPB2 | |
| SCHEMBL7510756 | 0.79 | ZDHHC7 (0.46) | MAPTCPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030092695-A1 | Metal salts of 3-methyl-chromane or thiochromane derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092695-A1 | Metal salts of 3-methyl-chromane or thiochromane derivatives | NR5A1, SHBG, ESR1 | ALDH1A1 3711/4885MAPT 1736/4885USP2 3184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.