SCHEMBL7074490

SCHEMBL7074490

O=C(S)N(Cc1ccccc1)NCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
ALDH1A1 P00352 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
THRB P10828 1/20 0.41
IDO1 P14902 1/20 0.41
HDAC3 O15379 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC2 Q92769 2/20 0.41
HDAC8 Q9BY41 2/20 0.41
NCOR2 Q9Y618 2/20 0.41
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41
GAA P10253 1/20 0.41
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3085177 0.87 NPC1 (0.48) NPC1RAB9AALDH1A1NPSR1KMT2A
SCHEMBL3081123 0.82 ALOX12 (0.50) ALDH1A1KMT2AMEN1THRBIDO1
SCHEMBL3075241 0.78 ALOX12 (0.48) ALDH1A1KMT2AMEN1THRBIDO1
SCHEMBL8581013 0.77 GAA (0.40) NPC1RAB9AALDH1A1NPSR1KMT2A
SCHEMBL28034055 0.76 LMNA (0.49) NPC1RAB9AALDH1A1KMT2AMEN1
SCHEMBL8843384 0.74 KDM4A (0.51) NPC1RAB9ANPSR1KMT2AMEN1
SCHEMBL3072971 0.72 LMNA (0.57) NPC1RAB9AALDH1A1NPSR1KMT2A
SCHEMBL11127626 0.72 ALOX5 (0.56) NPC1RAB9AALDH1A1NPSR1CA12
SCHEMBL9286682 0.72 ADH1B (0.40) NPC1RAB9AALDH1A1KMT2AMEN1
SCHEMBL3081125 0.71 GAA (0.49) ALDH1A1KMT2AMEN1IDO1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed