Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.57 |
| ▸ | TUBB | P07437 | 1/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.57 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.57 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.57 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.57 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.57 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.57 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074870 | 1.00 | TUBB4A (0.57) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL433921 | 0.81 | THRB (0.56) | THRBATMALDH1A1KDM4EMAPT | |
| SCHEMBL7820837 | 0.81 | THRB (0.56) | THRBATMALDH1A1KDM4EMAPT | |
| SCHEMBL2801414 | 0.81 | THRB (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7820839 | 0.81 | THRB (0.56) | THRBATMALDH1A1KDM4EMAPT | |
| SCHEMBL3661438 | 0.81 | THRB (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7072091 | 0.80 | NPC1 (0.47) | ALDH1A1HPGDTSHR | |
| SCHEMBL7072089 | 0.80 | NPC1 (0.47) | ALDH1A1HPGDTSHR | |
| SCHEMBL28499551 | 0.80 | MEN1 (0.64) | ALDH1A1KDM4EMAPTCYP1A2BCHE | |
| SCHEMBL20500020 | 0.79 | AKR1C3 (0.62) | THRBATMALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946492-B1 | NOVEL 2-FLUOROACRYLIC ACID DERIVATIVES, NOVEL MIXTURES OF HERBICIDES AND ANTIDOTES AND THE USE THEREOF | BAYER CROPSCIENCE GMBH (DE) | 2003-06-18 | — | — | EP | claimed |
| US-20210300902-A1 | OPTICALLY ACTIVE PYRROLIDINE COMPOUND AND METHOD FOR PRODUCING SAME | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2021-09-30 | — | — | US | disclosed |
| US-11053217-B2 | Optically active pyrrolidine compound and method for producing same | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2021-07-06 | — | — | US | disclosed |
| EP-3381913-B1 | 2-(((PYRROLIDIN-3-YL)CARBONYL)AMINO)-1H-IMIDAZOLE DERIVATIVES AS MELANOCORTIN RECEPTOR 1 (MCR1) AGONISTS FOR TREATING RHEUMATOID ARTHRITIS | MITSUBISHI TANABE PHARMA CORP (JP) | 2021-03-31 | — | — | EP | disclosed |
| CN-111592519-B | Fluorine-containing carboxylic acid compound and preparation method thereof | 四川大学 | 2021-03-23 | — | — | CN | disclosed |
| CN-111592519-A | Fluorine-containing carboxylic acid compound and preparation method thereof | 四川大学 | 2020-08-28 | — | — | CN | disclosed |
| US-20200239440-A1 | OPTICALLY ACTIVE PYRROLIDINE COMPOUND AND METHOD FOR PRODUCING SAME | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2020-07-30 | — | — | US | disclosed |
| US-9981960-B2 | Pyrrolidine compound and application as melanocortin receptor agonist | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2018-05-29 | — | — | US | disclosed |
| US-20170190697-A1 | NOVEL PYRROLIDINE COMPOUND AND APPLICATION AS MELANOCORTIN RECEPTOR AGONIST | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2017-07-06 | — | — | US | disclosed |
| WO-2017090743-A1 | NOVEL IMIDAZOLE COMPOUND AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONIST | 田辺三菱製薬株式会社 | 2017-06-01 | — | — | WO | disclosed |
| WO-2015182723-A1 | NOVEL PYRROLIDINE COMPOUND AND APPLICATION AS MELANOCORTIN RECEPTOR AGONIST | 田辺三菱製薬株式会社 | 2015-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11053217-B2 | Optically active pyrrolidine compound and method for producing same | ALDH18A1, DHPS, SRM | TUBB4A 760/4885TUBB 1098/4885TUBA3C 727/4885 |
| US-20210300902-A1 | OPTICALLY ACTIVE PYRROLIDINE COMPOUND AND METHOD FOR PRODUCING SAME | ALDH18A1, DHPS, SRM | TUBB4A 760/4885TUBB 1098/4885TUBA3C 727/4885 |
| US-20170190697-A1 | NOVEL PYRROLIDINE COMPOUND AND APPLICATION AS MELANOCORTIN RECEPTOR AGONIST | MC1R, MC5R, MC3R | TUBB4A 3891/4885TUBB 3839/4885TUBA3C 3704/4885 |
| US-20200239440-A1 | OPTICALLY ACTIVE PYRROLIDINE COMPOUND AND METHOD FOR PRODUCING SAME | ALDH18A1, DHPS, SRM | TUBB4A 760/4885TUBB 1098/4885TUBA3C 727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.