Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17120970 | 0.81 | MMP1 (0.43) | ALDH1A1GAASMN1; SMN2MMP1MMP2 | |
| SCHEMBL6611368 | 0.80 | CHRNB2 (0.35) | ALDH1A1GAASMN1; SMN2MMP1MMP2 | |
| SCHEMBL969221 | 0.79 | ALDH1A1 (0.43) | ALDH1A1GAASMN1; SMN2LMNAMMP1 | |
| SCHEMBL3934067 | 0.79 | ALDH1A1 (0.43) | ALDH1A1GAASMN1; SMN2LMNAMMP1 | |
| SCHEMBL3267958 | 0.75 | LMNA (0.37) | ALDH1A1SMN1; SMN2LMNAMMP1MMP2 | |
| SCHEMBL4420293 | 0.73 | CA12 (0.44) | ALDH1A1SMN1; SMN2LMNAMMP1MMP2 | |
| SCHEMBL9379383 | 0.72 | ALDH1A1 (0.38) | ALDH1A1GAASMN1; SMN2MMP1MMP2 | |
| SCHEMBL2605837 | 0.72 | ALDH1A1 (0.38) | ALDH1A1GAASMN1; SMN2MMP1MMP2 | |
| SCHEMBL28141911 | 0.72 | ALDH1A1 (0.42) | ALDH1A1GAASMN1; SMN2MMP1MMP2 | |
| SCHEMBL9475754 | 0.70 | ALDH1A1 (0.41) | ALDH1A1GAALMNAMMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212269-A1 | 4.5-disubstituted-2-aminopyrimidines | DAVIS JEREMY MARTIN (GB) | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212269-A1 | 4.5-disubstituted-2-aminopyrimidines | FLT1, FGFR1, FLT4 | ALDH1A1 3209/4885GAA 3579/4885SMN1; SMN2 3803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.