Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3934067 | 1.00 | ALDH1A1 (0.43) | ALDH1A1GAALMNAMMP1MMP2 | |
| SCHEMBL9475754 | 0.90 | ALDH1A1 (0.41) | ALDH1A1GAALMNAMMP1MMP2 | |
| SCHEMBL1416281 | 0.85 | ALDH1A1 (0.38) | ALDH1A1GAALMNAMMP1MMP2 | |
| SCHEMBL968823 | 0.85 | CA12 (0.43) | ALDH1A1GAALMNAMMP1MMP2 | |
| SCHEMBL7765563 | 0.84 | ALDH1A1 (0.42) | ALDH1A1GAALMNAMMP1MMP2 | |
| SCHEMBL9475748 | 0.83 | LMNA (0.40) | ALDH1A1LMNAMMP1MMP2MMP3 | |
| SCHEMBL11832724 | 0.82 | ALDH1A1 (0.36) | ALDH1A1GAALMNAMMP1MMP2 | |
| SCHEMBL965270 | 0.82 | CA12 (0.53) | ALDH1A1GAALMNAMMP1MMP2 | |
| SCHEMBL965052 | 0.82 | CA12 (0.43) | ALDH1A1GAALMNAMMP1MMP2 | |
| SCHEMBL11290100 | 0.81 | ALDH1A1 (0.42) | ALDH1A1GAAMMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9809565-B2 | Formation of chiral 4-chromanones using chiral pyrrolidines in the presence of ureas or thioureas | DSM IP ASSETS B.V. (NL) | 2017-11-07 | — | — | US | claimed |
| EP-1862198-B1 | Brightening and/or dyeing agent with urea derivatives | HENKEL AG & CO KGAA (DE) | 2017-04-05 | — | — | EP | claimed |
| EP-3016941-B1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF UREAS OR THIOUREAS | DSM IP ASSETS BV (NL) | 2017-03-22 | — | — | EP | claimed |
| US-20160145228-A1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF UREAS OR THIOUREAS | DSM IP ASSETS B.V. (NL) | 2016-05-26 | — | — | US | claimed |
| CN-105358540-A | Formation of chiral 4-chromanones using chiral pyrrolidines in the presence of ureas or thioureas | DSM IP ASSETS BV | 2016-02-24 | — | — | CN | claimed |
| EP-0331052-A2 | Process for the preparation of imidized acrylic polymers | ELF ATOCHEM ITALIA S.r.l. (IT) | 1989-09-06 | — | — | EP | claimed |
| US-20250368836-A1 | Polymer Thick Film Positive Temperature Coefficient Carbon Resistor Composition | CELANESE MERCURY HOLDINGS INC (US) | 2025-12-04 | — | — | US | disclosed |
| US-12351580-B2 | NLRP3 modulators | INNATE TUMOR IMMUNITY, INC. (US) | 2025-07-08 | — | — | US | disclosed |
| CN-119895628-A | Solvent and method for recycling fluids | 南洋理工大学 | 2025-04-25 | — | — | CN | disclosed |
| EP-4446310-A1 | METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND | Asahi Kasei Kabushiki Kaisha (JP) | 2024-10-16 | — | — | EP | disclosed |
| CN-118382612-A | Method for producing blocked isocyanate compound and method for producing isocyanate compound | 旭化成株式会社 | 2024-07-23 | — | — | CN | disclosed |
| US-20240067649-A1 | NLRP3 MODULATORS | INNATE TUMOR IMMUNITY INC (US) | 2024-02-29 | — | — | US | disclosed |
| US-11827632-B2 | NLRP3 modulators | INNATE TUMOR IMMUNITY, INC (US) | 2023-11-28 | — | — | US | disclosed |
| US-5459147-A | Angeotensin-antagonistic effects; hypotensive, antiischemic, and antidiabetic agents, treating glaucoma | DR. KARL THOMAE GMBH (DE) | 1995-10-17 | — | — | US | disclosed |
| US-5308743-A | USED IN THE MANUFACTURE OF SEMICONDUCTORS AND ELECTRONIC DEVICES | FUJI PHOTO FILM CO., LTD. (JP) | 1994-05-03 | — | — | US | disclosed |
| CN-1083812-A | Benzimidazoles contains the pharmaceutical composition of these compounds and their preparation | KRAL THOMAE GMBH (DE) | 1994-03-16 | — | — | CN | disclosed |
| US-5284745-A | Ripening, chemical sensitization under limited pH; rapid processing, latent-image stability, high contrast and sensitivity | FUJI PHOTO FILM CO., LTD. (JP) | 1994-02-08 | — | — | US | disclosed |
| US-5200310-A | Rapid processing, high sensitivity, good in safelight aptitude, wear resistance, pressure resistance | FUJI PHOTO FILM CO., LTD. (JP) | 1993-04-06 | — | — | US | disclosed |
| EP-0495659-A1 | A method for forming a dye image | KONICA CORPORATION (JP) | 1992-07-22 | — | — | EP | disclosed |
| US-4014876-A | HYPOGLYCEMIC | SHIONOGI & CO., LTD. (JA) | 1977-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827632-B2 | NLRP3 modulators | NLRP3, NLRP1, NOD1 | ALDH1A1 3584/4885GAA 3068/4885LMNA 3180/4885 |
| US-20160145228-A1 | FORMATION OF CHIRAL 4-CHROMANONES USING CHIRAL PYRROLIDINES IN THE PRESENCE OF UREAS OR THIOUREAS | UCK2, UMPS, HCCS | ALDH1A1 1356/4885GAA 3528/4885LMNA 4434/4885 |
| US-12351580-B2 | NLRP3 modulators | NLRP3, NLRP1, NOD1 | ALDH1A1 3584/4885GAA 3068/4885LMNA 3180/4885 |
| US-20240067649-A1 | NLRP3 MODULATORS | NLRP3, NLRP1, NOD1 | ALDH1A1 3584/4885GAA 3068/4885LMNA 3180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.