SCHEMBL707693

SCHEMBL707693

CCCC(C(F)(F)F)C(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10381190 0.89
SCHEMBL12251692 0.85
SCHEMBL16473070 0.85
SCHEMBL8354582 0.83
SCHEMBL7626563 0.81 DNM1 (0.39) TSHR
SCHEMBL9148426 0.79 OPRM1 (0.42) TSHR
SCHEMBL25161042 0.79
SCHEMBL4652996 0.77 LMNA (0.42) TSHR
SCHEMBL13557036 0.77 LMNA (0.42) TSHR
SCHEMBL8588299 0.77 LMNA (0.42) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 368 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1378534-A Substituted polycyclic aryl and heteroaryl pyridones for selective inhibition of the coagulation cascade PHARMACIA CO (US) 2002-11-06 CN claimed
CN-1351595-A Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade PHARMACIA CO (US) 2002-05-29 CN claimed
CN-1351594-A Substituted polycyclic aryl and heteroaryl uracils as anticoagulative agents PHARMACIA CORP (US) 2002-05-29 CN claimed
CN-1351593-A Substituted polycyclic aryl and heteroaryl pyrymidinones useful as anticoagulants agents PHARMACIA CO (US) 2002-05-29 CN claimed
US-5275669-A Degreasing glass, metal, plastic and fiber surfaces ALLIEDSIGNAL INC. (US) 1994-01-04 US claimed
CN-120040382-A Continuous synthesis and purification method and device for hexafluoropropylene oxide 浙江巨化汉正新材料有限公司 2025-05-27 CN disclosed
CN-119591753-A Method for purifying fluorine-containing polymer 衢州福聚电子材料有限公司 2025-03-11 CN disclosed
US-12035613-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240218004-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20240224782-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
CN-1351595-A Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade PHARMACIA CO (US) 2002-05-29 CN disclosed
CN-1351594-A Substituted polycyclic aryl and heteroaryl uracils as anticoagulative agents PHARMACIA CORP (US) 2002-05-29 CN disclosed
CN-1351593-A Substituted polycyclic aryl and heteroaryl pyrymidinones useful as anticoagulants agents PHARMACIA CO (US) 2002-05-29 CN disclosed
EP-1193309-A1 Solvent blend for use in high purity precursor removal AIR PRODUCTS AND CHEMICALS, INC. (US) 2002-04-03 EP disclosed
US-5944962-A OF LIQUID HYDROCARBONS USING ULTRAVIOLET RADIATION LAROCHE INDUSTRIES, INC. (US) 1999-08-31 US disclosed
WO-1999021870-A1 ERYTHROMYCIN A 11, 12-CARBAMATE DERIVATIVES TAISHO PHARMACEUTICAL CO., LTD. (JP) 1999-05-06 WO disclosed
US-5254755-A Solvents, cleaning compounds ALLIED-SIGNAL INC. (US) 1993-10-19 US disclosed
WO-1992010454-A1 PARTIALLY FLUORINATED ALKANOLS HAVING A TERTIARY STRUCTURE ALLIED-SIGNAL INC. (US) 1992-06-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG TSHR 2736/4885
US-12035613-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OTC TSHR 4305/4885
US-20240224782-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RER1, OCIAD2, OCIAD1 TSHR 596/4885
US-20240218004-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CCND2 TSHR 1707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.