Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7071992 | 0.77 | PIK3CD (0.31) | — | |
| SCHEMBL899400 | 0.74 | ADORA2A (0.32) | — | |
| SCHEMBL7072307 | 0.70 | — | — | |
| SCHEMBL7073225 | 0.67 | ADORA3 (0.30) | — | |
| SCHEMBL4440111 | 0.66 | MAPT (0.46) | — | |
| SCHEMBL15544686 | 0.65 | TLR8 (0.44) | — | |
| SCHEMBL7070793 | 0.65 | ADORA2A (0.35) | — | |
| SCHEMBL574806 | 0.60 | LTA4H (0.39) | HPGDS | |
| SCHEMBL3269209 | 0.59 | HPGDS (0.38) | HPGDSPDPK1 | |
| SCHEMBL8660614 | 0.59 | MAOA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349857-A1 | PURINE DERIVATIVES AS PURINERGIC RECEPTOR ANTAGONISTS | VERNALIS RESEARCH LIMITED (GB) | 2003-10-08 | — | — | EP | disclosed |
| WO-2002055521-A1 | PURINE DERIVATIVES AS PURINERGIC RECEPTOR ANTAGONISTS | VERNALIS RESEARCH LIMITED (GB) | 2002-07-18 | — | — | WO | disclosed |