Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.51 |
| ▸ | ABL1 | P00519 | 5/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.51 |
| ▸ | EGFR | P00533 | 4/20 | 0.51 |
| ▸ | HCK | P08631 | 4/20 | 0.51 |
| ▸ | KDR | P35968 | 4/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.51 |
| ▸ | MTOR | P42345 | 4/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.51 |
| ▸ | EPHB4 | P54760 | 4/20 | 0.51 |
| ▸ | PRKDC | P78527 | 4/20 | 0.51 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7830699 | 0.74 | NPC1 (0.42) | KDM4EALDH1A1HPGDSMN1; SMN2ADORA2A | |
| SCHEMBL544649 | 0.73 | ALDH1A1 (0.44) | SRCABL1KDRHSD17B10KDM4E | |
| SCHEMBL21721141 | 0.69 | MAPT (0.30) | MAPT | |
| SCHEMBL3845907 | 0.68 | KDM4E (0.46) | HSD17B10KDM4EALDH1A1HPGDPDE4A | |
| SCHEMBL6055041 | 0.68 | SRC (1.00) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL3850830 | 0.67 | L3MBTL1 (0.46) | HSD17B10KDM4EALDH1A1HPGDPDE4A | |
| SCHEMBL4867570 | 0.67 | L3MBTL1 (0.49) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL20522450 | 0.66 | KDM4E (0.49) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL30610428 | 0.66 | KDM4E (0.49) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL8840880 | 0.66 | PDE4A (0.67) | HSD17B10KDM4EALDH1A1HPGDPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003065971-A9 | NON-MYELOABLATIVE TOLEROGENIC TREATMENT WITH TYRPHOSTINS | YISSUM RES DEV CO (IL) | 2003-11-20 | — | — | WO | claimed |