Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31019388 | 0.81 | KIF11 (0.40) | HDAC1HDAC7HDAC8HDAC6EPHX2 | |
| SCHEMBL11404016 | 0.79 | ALDH1A1 (0.35) | IDO1MAPT | |
| SCHEMBL17681696 | 0.77 | CYP2A6 (0.36) | CA1CA2IDO1MAPT | |
| SCHEMBL6310114 | 0.77 | MAPT (0.38) | APPMAPT | |
| SCHEMBL11415130 | 0.77 | PDK1 (0.42) | HDAC1HDAC7HDAC8HDAC6CA1 | |
| SCHEMBL742856 | 0.76 | ALDH1A1 (0.39) | HDAC1HDAC7HDAC8HDAC6IDO1 | |
| SCHEMBL9095755 | 0.74 | GAA (0.52) | CA1CA2APPMAPT | |
| SCHEMBL31114495 | 0.67 | PDK1 (0.36) | HDAC1HDAC7HDAC8HDAC6EPHX2 | |
| SCHEMBL1310823 | 0.65 | HDAC1 (0.67) | TRPV1HDAC1HDAC7HDAC8HDAC6 | |
| SCHEMBL218036 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984920-B1 | NOVEL METHOD FOR PREPARING 2-TRIFLUORO-METHOXY-ANILINE | RHODIA CHIMIE SA (FR) | 2003-07-16 | — | — | EP | disclosed |
| US-6121492-A | Method for preparing 2-trifluoro-methoxy-aniline | RHODIA CHIMIE (FR) | 2000-09-19 | — | — | US | disclosed |
| EP-0984920-A1 | NOVEL METHOD FOR PREPARING 2-TRIFLUORO-METHOXY-ANILINE | RHODIA CHIMIE (FR) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998054121-A1 | NOVEL METHOD FOR PREPARING 2-TRIFLUORO-METHOXY-ANILINE | RHODIA-CHIMIE (FR) | 1998-12-03 | — | — | WO | disclosed |