Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6301730 | 0.87 | TRPM8 (0.42) | TRPM8ALDH1A1KDM4EMAPK1HSD17B10 | |
| SCHEMBL6295957 | 0.86 | ESR1 (0.36) | ALDH1A1GAAMAPTDRD2OPRM1 | |
| SCHEMBL7079047 | 0.80 | SIGMAR1 (0.35) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL7077467 | 0.79 | OPRM1 (0.34) | ALDH1A1MAPTDRD2DRD1DRD4 | |
| SCHEMBL7077864 | 0.79 | TRPM8 (0.43) | TRPM8ALDH1A1KDM4EMAPK1HSD17B10 | |
| SCHEMBL6295928 | 0.78 | ESRRG (0.32) | ALDH1A1GAARAB9ALMNASMN1; SMN2 | |
| SCHEMBL7080670 | 0.78 | LMNA (0.36) | ALDH1A1GAAMAPTOPRM1OPRK1 | |
| SCHEMBL7081436 | 0.77 | MTNR1B (0.32) | DRD2DRD1DRD4OPRM1DRD3 | |
| SCHEMBL7077373 | 0.77 | LMNA (0.33) | LMNASMN1; SMN2 | |
| SCHEMBL7081429 | 0.76 | TRPM8 (0.45) | TRPM8ALDH1A1KDM4EMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030171425-A1 | HIV protease inhibitors | BOYER FREDERICK EARL (US) | 2003-09-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171425-A1 | HIV protease inhibitors | DNPEP, PRSS1, PREP | TRPM8 4280/4885ALDH1A1 2323/4885KDM4E 1481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.