Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | NOS1 | P29475 | 3/20 | 0.40 |
| ▸ | NOS2 | P35228 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074326 | 0.86 | IDO1 (0.40) | TAAR1MAOBNOS1NOS2IDO1 | |
| SCHEMBL626371 | 0.81 | TAAR1 (0.64) | TAAR1MAOBIDO1HTR2A | |
| SCHEMBL14117328 | 0.80 | SIGMAR1 (0.40) | NOS1NOS2IDO1TACR1 | |
| Hydrochloric Acid SCHEMBL1970957 | 0.79 | TAAR1 (0.62) | TAAR1MAOBIDO1HTR2A | |
| SCHEMBL3950720 | 0.79 | MRGPRX4 (0.38) | NOS1NOS2IDO1TACR1 | |
| SCHEMBL3950360 | 0.79 | RXRA (0.42) | IDO1TACR1 | |
| SCHEMBL7694014 | 0.77 | TACR1 (0.43) | IDO1TACR1 | |
| SCHEMBL16515444 | 0.77 | TAAR1 (0.55) | TAAR1MAOBNOS1NOS2IDO1 | |
| SCHEMBL806196 | 0.74 | TAAR1 (0.56) | TAAR1MAOBIDO1HTR2A | |
| SCHEMBL43792 | 0.74 | TAAR1 (0.56) | TAAR1MAOBIDO1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030036653-A1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | AMERICAN HOME PRODUCTS CORPORATION | 2003-02-20 | — | — | US | disclosed |
| US-20020026055-A1 | Aminopyridine-containing thiourea inhibitors of herpes viruses | AMERICAN HOME PRODUCTS CORPORATION | 2002-02-28 | — | — | US | disclosed |
| US-20010039348-A1 | Alpha-methylbenzyl-containing thiourea inhibitors of herpes viruses containing a phenylenediamine group | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030036653-A1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | HAVCR2, CCR6, CXCR6 | TAAR1 211/4885MAOB 3776/4885NOS1 4151/4885 |
| US-20010039348-A1 | Alpha-methylbenzyl-containing thiourea inhibitors of herpes viruses containing a phenylenediamine group | CCR6, HAVCR2, BCOR | TAAR1 407/4885MAOB 2576/4885NOS1 2473/4885 |
| US-20020026055-A1 | Aminopyridine-containing thiourea inhibitors of herpes viruses | TK1, TPMT, CXCR6 | TAAR1 1159/4885MAOB 4517/4885NOS1 3126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.