Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563025 | 0.92 | IDO1 (0.46) | IDO1TDO2AOC3HDAC3HDAC4 | |
| SCHEMBL597442 | 0.92 | IDO1 (0.46) | NR3C1IDO1TDO2AOC3HDAC3 | |
| SCHEMBL7082143 | 0.83 | NR3C1 (0.43) | NR3C1AOC3KMT2AATMBRD4 | |
| SCHEMBL21542539 | 0.82 | EPHX1 (0.48) | NR3C1KMT2AATMKDM4EALDH1A1 | |
| SCHEMBL21542545 | 0.82 | EPHX1 (0.48) | NR3C1KMT2AATMKDM4EALDH1A1 | |
| SCHEMBL477477 | 0.82 | EPHX1 (0.48) | NR3C1KMT2AATMKDM4EALDH1A1 | |
| SCHEMBL21831203 | 0.80 | NR3C1 (0.44) | NR3C1IDO1TDO2AOC3HDAC3 | |
| SCHEMBL5518530 | 0.80 | IGF1R (0.46) | NR3C1IDO1TDO2AOC3HDAC3 | |
| SCHEMBL1349994 | 0.80 | TSHR (0.42) | NR3C1ATMLMNASMN1; SMN2 | |
| SCHEMBL21831189 | 0.80 | ACHE (0.62) | NR3C1AOC3KMT2AATMBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030114692-A1 | Method for the preparation of citalopram | H. LUNDBECK A/S (DK) | 2003-06-19 | — | — | US | disclosed |
| US-20030083508-A1 | Method for the preparation of citalopram | H. LUNDBECK A/S (DK) | 2003-05-01 | — | — | US | disclosed |
| EP-1259500-A1 | METHOD FOR THE PREPARATION OF CITALOPRAM | H. Lundbeck A/S (DK) | 2002-11-27 | — | — | EP | disclosed |
| US-20020004604-A1 | Method for the preparation of citalopram | H. LUNDBECK A/S (DK) | 2002-01-10 | — | — | US | disclosed |
| WO-2001062754-A1 | METHOD FOR THE PREPARATION OF CITALOPRAM | H. LUNDBECK A/S (DK) | 2001-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083508-A1 | Method for the preparation of citalopram | MAOB, MAOA, TPH1 | NR3C1 1036/4885IDO1 144/4885TDO2 886/4885 |
| US-20020004604-A1 | Method for the preparation of citalopram | MAOB, MAOA, TPH1 | NR3C1 1036/4885IDO1 144/4885TDO2 886/4885 |
| US-20030114692-A1 | Method for the preparation of citalopram | MAOB, MAOA, TPH1 | NR3C1 1036/4885IDO1 144/4885TDO2 886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.