Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683844 | 0.85 | MEN1 (0.38) | ALDH1A1MEN1KMT2ALMNANPC1 | |
| SCHEMBL7813283 | 0.79 | HSD11B1 (0.44) | P2RX7ALDH1A1HPGDEPHX2MAPK1 | |
| SCHEMBL7079121 | 0.77 | HSD11B1 (0.40) | ALDH1A1TSHRHPGDKDM4EKMT2A | |
| SCHEMBL6680932 | 0.77 | GRIN2D (0.39) | EPHX2FPR1 | |
| SCHEMBL6684561 | 0.77 | EPHX2 (0.36) | P2RX7ALDH1A1HPGDEPHX2MAPK1 | |
| SCHEMBL29244325 | 0.76 | FAAH (0.35) | P2RX7ALDH1A1TSHRHPGDEPHX2 | |
| Hydrochloric Acid SCHEMBL6680842 | 0.76 | HTR2C (0.38) | — | |
| SCHEMBL7078031 | 0.75 | GRIN2D (0.42) | NPC1RAB9A | |
| SCHEMBL29173828 | 0.74 | P2RX7 (0.63) | P2RX7EPHX2MEN1KMT2A | |
| SCHEMBL7085776 | 0.74 | GRIN2D (0.44) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003064372-A1 | 2-ADAMANTYLALKYLAMINES AND THEIR USE IN THE TREATMENT OF CONDITIONS GENERALLY ASSOCIATED WITH ABNORMALITIES IN GLUTAMATERGIC TRANSMISSION | VERNALIS RESEARCH LIMITED (GB) | 2003-08-07 | — | — | WO | disclosed |