Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825363 | 0.88 | HSD11B1 (0.49) | HSD11B1P2RX7ALDH1A1LMNAHPGD | |
| SCHEMBL7834125 | 0.87 | HSD11B1 (0.50) | HSD11B1P2RX7ALDH1A1MEN1KMT2A | |
| SCHEMBL29173828 | 0.86 | P2RX7 (0.63) | P2RX7MEN1KMT2AEPHX2 | |
| SCHEMBL6684561 | 0.80 | EPHX2 (0.36) | P2RX7ALDH1A1HPGDFAAHMAPK1 | |
| SCHEMBL7079611 | 0.79 | P2RX7 (0.36) | P2RX7ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL12705238 | 0.77 | ALDH1A1 (0.36) | P2RX7ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL6680932 | 0.77 | GRIN2D (0.39) | EPHX2 | |
| SCHEMBL19149260 | 0.76 | FAAH (0.41) | P2RX7ALDH1A1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL6680842 | 0.76 | HTR2C (0.38) | — | |
| SCHEMBL3510746 | 0.75 | ALDH1A1 (0.40) | HSD11B1P2RX7ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| EP-0702689-A4 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR 3-PHENYL-1-ADAMANTANEACETIC ACIDS | ABBOTT LAB (US) | 1997-10-22 | — | — | EP | disclosed |
| EP-0702689-A1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR 3-PHENYL-1-ADAMANTANEACETIC ACIDS | ABBOTT LABORATORIES (US) | 1996-03-27 | — | — | EP | disclosed |
| WO-1994029329-A1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR 3-PHENYL-1-ADAMANTANEACETIC ACIDS | ABBOTT LABORATORIES (US) | 1994-12-22 | — | — | WO | disclosed |