SCHEMBL7080205

SCHEMBL7080205

COC(=O)CC(=O)CCc1cccc(F)c1

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.49
FFAR1 O14842 1/20 0.47
ALOX5 P09917 1/20 0.46
OR51E2 Q9H255 1/20 0.46
CNR1 P21554 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
F2RL1 P55085 1/20 0.44
IDO1 P14902 1/20 0.44
AGXT P21549 1/20 0.44
MRGPRX4 Q96LA9 1/20 0.43
NR3C2 P08235 1/20 0.43
MAOB P27338 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL901672 0.89 TAAR1 (0.53) TAAR1FFAR1MRGPRX4NR3C2MAOB
SCHEMBL11066194 0.87 NPC1 (0.46) TAAR1FFAR1ALOX5CNR1MEN1
SCHEMBL13237150 0.84 VNN1 (0.47) TAAR1MEN1KMT2AIDO1AGXT
SCHEMBL7340106 0.84 TAAR1 (0.57) TAAR1FFAR1CNR1NR3C2
SCHEMBL27973686 0.83 SPR (0.54) TAAR1ALOX5OR51E2F2RL1
SCHEMBL11073323 0.83 HCAR2 (0.49) TAAR1FFAR1
SCHEMBL26343023 0.83 FFAR1 (0.57) TAAR1FFAR1CNR1NR3C2
SCHEMBL3944516 0.82 MAOB (0.52) MEN1KMT2AMRGPRX4MAOB
SCHEMBL23901663 0.81 IAPP (0.56) TAAR1FFAR1CNR1NR3C2MAOB
SCHEMBL755111 0.81 F2RL1 (0.57) FFAR1ALOX5OR51E2F2RL1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230303493-A1 ANTIBACTERIAL ADJUVANTS AND APPLICATIONS THEREOF SAN JOSE STATE UNIVERSITY RESEARCH FOUNDATION 2023-09-28 US disclosed
US-20030236302-A1 Synthetic derivatives SYNTA PHARMACEUTICALS CORP. 2003-12-25 US disclosed
WO-2003072103-A1 SYNTHETIC DERIVATIVES KAVA PHARMACEUTICALS, INC. (US) 2003-09-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303493-A1 ANTIBACTERIAL ADJUVANTS AND APPLICATIONS THEREOF CAPG, SLC11A2, CAPRIN1 TAAR1 4154/4885FFAR1 2959/4885ALOX5 1472/4885
US-20030236302-A1 Synthetic derivatives CBR1, CBR3, REL TAAR1 435/4885FFAR1 583/4885ALOX5 249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.