Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795589 | 0.89 | ALDH1A1 (0.45) | CYP3A4NPC1RAB9APOLBMEN1 | |
| SCHEMBL6502168 | 0.84 | NPC1 (0.51) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL6501075 | 0.82 | RAB9A (0.43) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL7084303 | 0.82 | NPC1 (0.44) | CYP3A4NPC1RAB9APOLBL3MBTL1 | |
| SCHEMBL6489781 | 0.81 | L3MBTL1 (0.47) | CYP3A4POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL6789124 | 0.81 | TP53 (0.50) | TP53MAPTHTTLMNA | |
| SCHEMBL6492508 | 0.81 | SMN1; SMN2 (0.52) | CYP3A4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6499843 | 0.81 | SMN1; SMN2 (0.47) | NPC1RAB9APOLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7079728 | 0.80 | SMN1; SMN2 (0.51) | CYP3A4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6669283 | 0.80 | MAPT (0.43) | NPC1RAB9APOLBL3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |