Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | APOB | P04114 | 1/20 | 0.40 |
| ▸ | MTTP | P55157 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795383 | 0.89 | LMNA (0.52) | LMNAHTTTRPV1SMOAPOB | |
| SCHEMBL7131826 | 0.85 | DGAT2 (0.48) | LMNAMAPTTRPV1KDM4EMAPK1 | |
| SCHEMBL7138922 | 0.83 | LMNA (0.61) | LMNAHTTMAPTMEN1KMT2A | |
| SCHEMBL7086824 | 0.83 | LMNA (0.48) | LMNAHTTMAPTMEN1KMT2A | |
| SCHEMBL6663855 | 0.81 | SRPK1 (0.43) | LMNAMAPTSRPK1SMOAPOB | |
| SCHEMBL7086631 | 0.77 | NPC1 (0.54) | LMNARXFP1NPC1RAB9AAPOB | |
| SCHEMBL6789936 | 0.76 | ADAMTS7 (0.49) | TRPV1SMOAPOBMTTP | |
| SCHEMBL7133291 | 0.76 | NPC1 (0.56) | LMNATRPV1KDM4EMAPK1NPC1 | |
| SCHEMBL6792746 | 0.76 | PTGS1 (0.57) | LMNANPC1RAB9AAPOBMTTP | |
| SCHEMBL6794781 | 0.76 | RAB9A (0.46) | LMNAMAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |