Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7080892 | 0.73 | LMNA (0.38) | LMNAKMT2A | |
| Acetic Acid SCHEMBL9574999 | 0.73 | ALDH1A1 (0.45) | ACLYALDH1A1GAALMNATSHR | |
| SCHEMBL9423113 | 0.72 | ACLY (0.38) | ACLYALDH1A1GAALMNATSHR | |
| SCHEMBL7081979 | 0.72 | ACLY (0.38) | ACLYALDH1A1GAA | |
| SCHEMBL2921575 | 0.71 | KEAP1 (0.46) | ACLYALDH1A1GAALMNATSHR | |
| SCHEMBL6264568 | 0.70 | SRC (0.43) | ACLYALDH1A1GAALMNATSHR | |
| SCHEMBL6639307 | 0.69 | LMNA (0.42) | ACLYALDH1A1GAALMNATSHR | |
| SCHEMBL10901164 | 0.69 | ACLY (0.44) | ACLYALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL8382631 | 0.68 | ALDH1A1 (0.41) | ALDH1A1GAALMNATSHRSMN1; SMN2 | |
| SCHEMBL8378149 | 0.68 | ALDH1A1 (0.41) | ALDH1A1GAALMNATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592439-B1 | AMINOSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 2003-07-30 | — | — | EP | claimed |