Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | MMP3 | P08254 | 3/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP7 | P09237 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8382631 | 1.00 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2GAAMMP2MMP3 | |
| SCHEMBL8415723 | 0.71 | HTT (0.54) | SMN1; SMN2MEN1KMT2AMMELMNA | |
| SCHEMBL8381845 | 0.71 | KDM4E (0.49) | MMP2MMP3MMP13MMP1MMP7 | |
| SCHEMBL12757448 | 0.71 | LMNA (0.53) | ALDH1A1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL8746476 | 0.71 | KDM4E (0.49) | MMP2MMP3MMP13MMP1MMP7 | |
| SCHEMBL8381843 | 0.71 | KDM4E (0.49) | MMP2MMP3MMP13MMP1MMP7 | |
| SCHEMBL10901164 | 0.71 | ACLY (0.44) | ALDH1A1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL9119484 | 0.70 | LMNA (0.51) | ALDH1A1GAAMEN1KMT2ALMNA | |
| SCHEMBL9331274 | 0.69 | CTSK (0.53) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL7318689 | 0.69 | LMNA (0.51) | SMN1; SMN2MEN1KMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758317-B1 | N-SULPHONYL AND N-SULPHINYL AMINO ACID AMIDES AS MICROBIOCIDES | NOVARTIS AG (CH) | 1999-04-07 | — | — | EP | disclosed |
| US-5728875-A | FUNGICIDES FOR CROPS FORMED BY AMIDATION AND OXIDATION | NOVARTIS CORPORATION (US) | 1998-03-17 | — | — | US | disclosed |
| EP-0758317-A1 | N-SULPHONYL AND N-SULPHINYL AMINO ACID AMIDES AS MICROBIOCIDES | Novartis AG (CH) | 1997-02-19 | — | — | EP | disclosed |
| US-5585519-A | FUNGICIDE | CIBA-GEIGY CORPORATION (US) | 1996-12-17 | — | — | US | disclosed |