Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.79 |
| ▸ | RAB9A | P51151 | 4/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2301959 | 0.88 | KMT2A (0.64) | NPC1RAB9AKMT2AHTTL3MBTL1 | |
| SCHEMBL17010765 | 0.86 | L3MBTL1 (0.62) | NPC1RAB9AKMT2AHTTL3MBTL1 | |
| SCHEMBL12715452 | 0.82 | ALDH1A1 (0.63) | NPC1RAB9AKMT2AHTTL3MBTL1 | |
| SCHEMBL15979736 | 0.79 | NPC1 (0.76) | NPC1RAB9AKMT2AHTTL3MBTL1 | |
| SCHEMBL8208699 | 0.79 | CYP1A2 (0.64) | NPC1RAB9AKMT2AHTTL3MBTL1 | |
| SCHEMBL1898771 | 0.79 | NPC1 (1.00) | NPC1RAB9AKMT2AHTTL3MBTL1 | |
| SCHEMBL29356203 | 0.79 | NPC1 (1.00) | NPC1RAB9AKMT2AHTTL3MBTL1 | |
| SCHEMBL873499 | 0.78 | TSHR (0.71) | NPC1RAB9AKMT2AHTTL3MBTL1 | |
| SCHEMBL6895565 | 0.78 | ALDH1A1 (0.58) | NPC1RAB9AKMT2AHTTL3MBTL1 | |
| SCHEMBL29678391 | 0.78 | TSHR (0.71) | NPC1RAB9AKMT2AHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610738-B2 | Treatment of Alzheimer's Disease by combining both acetylcholinesterase inhibitory activity and antioxidant activity (by virtue of their carbamoyl and flavonoid pharmacophores) | BIOGAL PHARMACEUTICAL CO., LTD. (HU) | 2003-08-26 | — | — | US | disclosed |
| EP-1322632-A1 | N-DISUBSTITUTED CARBAMOYLOXY FLAVONES | Biogal Pharmaceutical Co., Ltd (HU) | 2003-07-02 | — | — | EP | disclosed |
| US-20020128494-A1 | N-Disubstituted carbamoyloxy flavones | BIOGAL PHARMACEUTICAL CO., LTD. (HU) | 2002-09-12 | — | — | US | disclosed |
| WO-2002024677-A1 | N-DISUBSTITUTED CARBAMOYLOXY FLAVONES | BIOGAL PHARMACEUTICAL CO., LTD. (HU) | 2002-03-28 | — | — | WO | disclosed |
| WO-2002024676-A1 | N-DISUBSTITUTED CARBAMOYLOXY FLAVONES | TEVA PHARMACEUTICALS INDUSTRIES, LTD. (IL) | 2002-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128494-A1 | N-Disubstituted carbamoyloxy flavones | CBR3, FOS, CBR1 | NPC1 1055/4885RAB9A 709/4885KMT2A 2515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.