SCHEMBL17010765

SCHEMBL17010765

O=C(COC(=O)c1ccccc1OCC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.62
TDP1 Q9NUW8 2/20 0.62
CYP1A2 P05177 2/20 0.61
CYP2C9 P11712 2/20 0.61
CYP2C19 P33261 2/20 0.61
RAB9A P51151 5/20 0.59
NPC1 O15118 4/20 0.59
MAPT P10636 5/20 0.57
LMNA P02545 5/20 0.57
HTT P42858 2/20 0.57
MEN1 O00255 5/20 0.56
KMT2A Q03164 5/20 0.56
NPSR1 Q6W5P4 3/20 0.56
HPGD P15428 1/20 0.54
ALDH1A1 P00352 1/20 0.54
PKM P14618 1/20 0.53
CYP3A4 P08684 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
ATM Q13315 1/20 0.52
GPR55 Q9Y2T6 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7082017 0.86 NPC1 (0.79) L3MBTL1CYP1A2CYP2C9CYP2C19RAB9A
SCHEMBL14398436 0.85 KDM4E (0.67) L3MBTL1TDP1CYP1A2CYP2C9CYP2C19
SCHEMBL9787048 0.82 L3MBTL1 (0.73) L3MBTL1TDP1CYP1A2CYP2C9CYP2C19
SCHEMBL855090 0.82 MAPT (0.78) L3MBTL1TDP1CYP1A2CYP2C9CYP2C19
SCHEMBL8208699 0.80 CYP1A2 (0.64) L3MBTL1TDP1CYP1A2CYP2C9CYP2C19
SCHEMBL13550378 0.79 ALDH1A1 (0.60) L3MBTL1TDP1CYP1A2CYP2C9CYP2C19
SCHEMBL29112376 0.79 CYP1A2 (0.67) L3MBTL1CYP1A2CYP2C9CYP2C19RAB9A
SCHEMBL83331 0.79 RAB9A (0.79) L3MBTL1TDP1RAB9ANPC1MAPT
SCHEMBL2301959 0.78 KMT2A (0.64) L3MBTL1CYP1A2CYP2C9CYP2C19RAB9A
SCHEMBL9422635 0.77 MAPT (0.55) L3MBTL1TDP1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3104835-B1 PULVURENT EFFERVESCENT TOPICAL TREATMENT COMPOSITION RECKITT BENCKISER LLC (US) 2019-02-13 EP disclosed
US-9877484-B2 Pulvurent effervescent topical treatment composition RECKITT BENCKISER LLC (US) 2018-01-30 US disclosed
US-20170006874-A1 PULVURENT EFFERVESCENT TOPICAL TREATMENT COMPOSITION RECKITT BENCKISER LLC (US) 2017-01-12 US disclosed
EP-3104835-A1 PULVURENT EFFERVESCENT TOPICAL TREATMENT COMPOSITION Reckitt Benckiser LLC (US) 2016-12-21 EP disclosed
WO-2015121659-A1 PULVURENT EFFERVESCENT TOPICAL TREATMENT COMPOSITION RECKITT BENCKISER LLC (US) 2015-08-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170006874-A1 PULVURENT EFFERVESCENT TOPICAL TREATMENT COMPOSITION SOST, FPR2, SHH L3MBTL1 3586/4885TDP1 4572/4885CYP1A2 2320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.