Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.52 |
| ▸ | BCR | P11274 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47861 | 0.88 | TSHR (0.56) | HSD17B1HSD17B2MAPK1TP53TSHR | |
| SCHEMBL13695146 | 0.84 | TSHR (0.48) | HSD17B1HSD17B2MAPK1TSHRCASP1 | |
| SCHEMBL7084047 | 0.82 | HSD17B1 (0.68) | ABL1ABCB1BCRGAAHSD17B1 | |
| SCHEMBL12387990 | 0.81 | APP (0.70) | TSHRCASP1APPACHETRPA1 | |
| SCHEMBL14295102 | 0.81 | MCL1 (0.57) | HSD17B1HSD17B2MAPK1TSHRCASP1 | |
| SCHEMBL1007614 | 0.79 | MCL1 (0.52) | HSD17B1HSD17B2MAPK1TP53TSHR | |
| SCHEMBL31344493 | 0.79 | HSD17B1 (0.59) | HSD17B1HSD17B2MAPK1TP53TSHR | |
| SCHEMBL31212445 | 0.79 | HSD17B1 (0.59) | HSD17B1HSD17B2MAPK1TP53TSHR | |
| SCHEMBL29319710 | 0.78 | ABL1 (0.48) | ABL1ABCB1BCRGAAHSD17B1 | |
| SCHEMBL25420702 | 0.78 | APP (0.74) | ABL1ABCB1BCRHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030139479-A1 | Non-halogenated biphenyl triol compounds, antimicrobial compositions containing the same, and methods of using the same | WARNER-LAMBERT COMPANY | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139479-A1 | Non-halogenated biphenyl triol compounds, antimicrobial compositions containing the same, and methods of using the same | AS3MT, PTPN1, NONO | ABL1 157/4885ABCB1 105/4885BCR 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.