Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 13/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | CLK3 | P49761 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | PNCK | Q6P2M8 | 1/20 | 0.40 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10019585 | 0.89 | DYRK1A (0.49) | DYRK1AAURKAHSP90AA1PRKACAADORA2A | |
| SCHEMBL10019584 | 0.88 | DYRK1A (0.48) | DYRK1AAURKAHSP90AA1PRKACAADORA2A | |
| SCHEMBL10019586 | 0.85 | DYRK1A (0.41) | DYRK1APDPK1AURKAHSP90AA1PRKACA | |
| SCHEMBL28886710 | 0.85 | AURKA (0.55) | DYRK1APDPK1AURKAHSP90AA1PRKACA | |
| SCHEMBL12073354 | 0.80 | AURKA (0.53) | DYRK1AAURKAHSP90AA1PRKACAADORA2A | |
| SCHEMBL709817 | 0.80 | CTSK (0.43) | AURKAHSP90AA1PRKACAADORA2AKMT2A | |
| SCHEMBL712182 | 0.79 | HSP90AA1 (0.69) | DYRK1APDPK1AURKAHSP90AA1PRKACA | |
| SCHEMBL10973666 | 0.77 | GSK3B (0.55) | DYRK1AAURKAHSP90AA1PRKACAADORA2A | |
| SCHEMBL10918699 | 0.74 | DYRK1A (0.53) | DYRK1APDPK1DYRK3CLK1CLK2 | |
| SCHEMBL17942909 | 0.74 | LTB4R (0.49) | MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124762-B2 | Diphenyl amine derivatives having luminescence property | KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2012-02-28 | — | — | US | disclosed |
| US-8124762-B2 | Diphenyl amine derivatives having luminescence property | KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2012-02-28 | — | — | US | disclosed |
| US-8124762-B2 | Diphenyl amine derivatives having luminescence property | KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2012-02-28 | — | — | US | disclosed |
| US-20100063281-A1 | DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY | KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2010-03-11 | — | — | US | disclosed |
| US-20100063281-A1 | DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY | KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2010-03-11 | — | — | US | disclosed |
| US-20100063281-A1 | DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY | KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063281-A1 | DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY | TYR, PNMT, DDC | DYRK1A 583/4885PDPK1 1686/4885AURKA 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.