Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.69 |
| ▸ | AURKA | O14965 | 2/20 | 0.69 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.69 |
| ▸ | PRKACA | P17612 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12176972 | 0.86 | HSP90AA1 (0.92) | HSP90AA1AURKAADORA2APRKACARAB9A | |
| SCHEMBL316210 | 0.82 | HSP90AA1 (1.00) | HSP90AA1AURKAADORA2APRKACARAB9A | |
| SCHEMBL710851 | 0.81 | AURKA (0.44) | HSP90AA1AURKAADORA2APRKACARAB9A | |
| Hydrochloric Acid SCHEMBL17186384 | 0.81 | HSP90AA1 (0.96) | HSP90AA1AURKAADORA2APRKACARAB9A | |
| SCHEMBL708351 | 0.79 | DYRK1A (0.48) | HSP90AA1AURKAADORA2APRKACACYP1A2 | |
| SCHEMBL10019585 | 0.78 | DYRK1A (0.49) | HSP90AA1AURKAADORA2APRKACARAB9A | |
| SCHEMBL10019584 | 0.77 | DYRK1A (0.48) | HSP90AA1AURKAADORA2APRKACARAB9A | |
| SCHEMBL28013042 | 0.75 | HSP90AA1 (0.71) | HSP90AA1AURKAADORA2APRKACARAB9A | |
| SCHEMBL21164006 | 0.75 | HSP90AA1 (0.70) | HSP90AA1AURKAADORA2APRKACARAB9A | |
| SCHEMBL709831 | 0.75 | IKBKB (0.59) | JAK3GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124762-B2 | Diphenyl amine derivatives having luminescence property | KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2012-02-28 | — | — | US | disclosed |
| US-8124762-B2 | Diphenyl amine derivatives having luminescence property | KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2012-02-28 | — | — | US | disclosed |
| US-8124762-B2 | Diphenyl amine derivatives having luminescence property | KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2012-02-28 | — | — | US | disclosed |
| US-20100063281-A1 | DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY | KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2010-03-11 | — | — | US | disclosed |
| US-20100063281-A1 | DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY | KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2010-03-11 | — | — | US | disclosed |
| US-20100063281-A1 | DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY | KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063281-A1 | DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY | TYR, PNMT, DDC | HSP90AA1 4693/4885AURKA 235/4885ADORA2A 895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.