Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086092 | 0.90 | LMNA (0.35) | SMN1; SMN2HTTPOLBALDH1A1LMNA | |
| SCHEMBL7084176 | 0.87 | SMN1; SMN2 (0.38) | SMN1; SMN2L3MBTL1ACSS2HTTPOLB | |
| SCHEMBL6975217 | 0.87 | TP53 (0.39) | SMN1; SMN2L3MBTL1HTTPOLBMTNR1A | |
| SCHEMBL7084094 | 0.86 | SMN1; SMN2 (0.40) | SMN1; SMN2L3MBTL1POLBMTNR1AMTNR1B | |
| SCHEMBL7082939 | 0.85 | SMN1; SMN2 (0.31) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7082255 | 0.85 | ALDH1A1 (0.41) | SMN1; SMN2L3MBTL1POLBALDH1A1MEN1 | |
| SCHEMBL6964218 | 0.84 | SMN1; SMN2 (0.35) | SMN1; SMN2L3MBTL1ACSS2HTTPOLB | |
| SCHEMBL6967170 | 0.84 | SMN1; SMN2 (0.35) | SMN1; SMN2L3MBTL1ACSS2HTTPOLB | |
| SCHEMBL6965884 | 0.84 | ALDH1A1 (0.41) | SMN1; SMN2L3MBTL1HTTPOLBALDH1A1 | |
| SCHEMBL6966426 | 0.84 | IRAK4 (0.39) | SMN1; SMN2L3MBTL1POLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |