Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 17/20 | 0.67 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.57 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085648 | 0.82 | LMNA (0.64) | SERPINE1SLC6A9SLC6A5MEN1KMT2A | |
| SCHEMBL7325216 | 0.80 | MPO (0.83) | MEN1KMT2AMPO | |
| SCHEMBL7089125 | 0.80 | SERPINE1 (1.00) | SERPINE1SLC6A9SLC6A5 | |
| SCHEMBL1421137 | 0.79 | SERPINE1 (1.00) | SERPINE1SLC6A9SLC6A5 | |
| SCHEMBL7088271 | 0.76 | SERPINE1 (0.73) | SERPINE1 | |
| SCHEMBL7088383 | 0.76 | SERPINE1 (0.69) | SERPINE1SLC6A9SLC6A5MEN1KMT2A | |
| SCHEMBL4249335 | 0.75 | CTSV (0.71) | MEN1KMT2AMPO | |
| SCHEMBL7088443 | 0.75 | SERPINE1 (0.90) | SERPINE1SLC6A9SLC6A5 | |
| SCHEMBL3932988 | 0.73 | SLC6A9 (1.00) | SLC6A9SLC6A5 | |
| SCHEMBL7088252 | 0.72 | SERPINE1 (0.77) | SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080060-A1 | SUBSTITUTED PIPERAZINE ANTITHROMBOTIC PAI-1 INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |