SCHEMBL708581

SCHEMBL708581

CC(O)[C@H](NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTSK P43235 9/20 0.51
CTSS P25774 5/20 0.51
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CYP2D6 P10635 1/20 0.46
APP P05067 1/20 0.45
TSHR P16473 1/20 0.43
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
KMT2A Q03164 1/20 0.42
CTSL P07711 2/20 0.42
CTSB P07858 2/20 0.42
PREP P48147 1/20 0.41
TRPA1 O75762 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1312767 1.00 CTSK (0.51) CTSKCTSSCA1CA2CA7
SCHEMBL999110 1.00 CTSK (0.51) CTSKCTSSCA1CA2CA7
SCHEMBL16710007 1.00 CTSK (0.51) CTSKCTSSCA1CA2CA7
SCHEMBL1312765 1.00 CTSK (0.51) CTSKCTSSCA1CA2CA7
SCHEMBL708582 1.00 CTSK (0.51) CTSKCTSSCA1CA2CA7
SCHEMBL693616 1.00 CTSK (0.51) CTSKCTSSCA1CA2CA7
SCHEMBL1311851 1.00 CTSK (0.51) CTSKCTSSCA1CA2CA7
SCHEMBL23794778 0.89 CTSK (0.49) CTSKCTSSCA1CA2CA7
SCHEMBL30718547 0.89 CTSK (0.49) CTSKCTSSCA1CA2CA7
SCHEMBL23794776 0.89 CTSK (0.49) CTSKCTSSCA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242572-A1 a-CARBONYL ALKENYL ESTER PREPARATION METHOD THEREFOR AND APPLICATION THEREOF JIANGXI NORMAL UNIVERSITY (CN) 2023-08-03 US claimed
CN-115252806-A Preparation method of nano-drug carrier G5-R with high-efficiency tumor penetration capacity 浙江大学杭州国际科创中心 2022-11-01 CN claimed
EP-4043447-B1 HALOGENATED TETRACYCLIC TRITERPENE DERIVATIVE, PREPARATION AND APPLICATION THEREOF SHANGHAI QINGDONG BIOTECHNOLOGY CO LTD (CN) 2026-01-21 EP disclosed
US-20260014146-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS INC (US) 2026-01-15 US disclosed
US-20250304603-A1 OXABOROLE ESTERS AND USES THEREOF ANACOR PHARMACEUTICALS INC (US) 2025-10-02 US disclosed
US-20250110407-A1 SEMICONDUCTOR SUBSTRATE MANUFACTURING METHOD, AND RESIST BASE FILM FORMING COMPOSITION JSR CORPORATION (JP) 2025-04-03 US disclosed
US-20250002495-A1 SPIRO-LACTAM NMDA MODULATORS AND METHODS OF USING SAME TENACIA BIOTECHNOLOGY HONG KONG CO LTD (HK) 2025-01-02 US disclosed
US-12157736-B2 Spiro-lactam NMDA modulators and methods of using same TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (HK) 2024-12-03 US disclosed
CN-118930602-A Method for performing terminal allylation modification on natural amino acid or polypeptide 南京工业大学 2024-11-12 CN disclosed
US-12084444-B2 Spiro-lactam NMDA modulators and methods of using same TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (CN) 2024-09-10 US disclosed
US-20240294489-A1 LOW MOLECULAR WEIGHT PROTEIN DEGRADERS AND THEIR APPLICATIONS CAPTOR THERAPEUTICS S.A. (PL) 2024-09-05 US disclosed
US-4833076-A ANTITUMOR AGENTS BRISTOL-MYERS COMPANY (US) 1989-05-23 US disclosed
US-4808579-A 3-(2-(2-AMINO-4-THIAZOLYL))-2-METHOXYIMINOACETYLAMINO-2-OXO-1-AZETIDINYLIMINOACETIC ACID AMERICAN CYANAMID COMPANY (US) 1989-02-28 US disclosed
US-4789731-A Semi-synthetic peptide antibiotics BRISTOL-MYERS COMPANY (US) 1988-12-06 US disclosed
US-4742047-A ANTITUMOR BRISTOL-MYERS COMPANY (US) 1988-05-03 US disclosed
US-4692510-A ANTIBIOTICS, ANTITUMOR AGENTS BRISTOL-MYERS COMPANY (US) 1987-09-08 US disclosed
US-4681937-A 3-acylamino-2-oxo-1-azetidinyl esters of phosphonic acids, phosphoric acid and phosphoric acid esters E. R. SQUIBB & SONS, INC. (US) 1987-07-21 US disclosed
US-4551276-A 2-Oxoazetidin-1-yloxymethyl sulfonic acid and analogs E. R. SQUIBB & SONS, INC. (US) 1985-11-05 US disclosed
US-4382142-A ANTITUMOR AND ANTICARCINOGENIC AGENTS; LEUKEMIA KOWA CO., LTD. (JP) 1983-05-03 US disclosed
US-4013565-A MEMBRANES RHONE-POULENC S.A. (FR) 1977-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240294489-A1 LOW MOLECULAR WEIGHT PROTEIN DEGRADERS AND THEIR APPLICATIONS MMP2, PSME2, PSME1 CTSK 683/4885CTSS 636/4885CA1 3278/4885
US-20250304603-A1 OXABOROLE ESTERS AND USES THEREOF OXA1L, HSD17B12, OXER1 CTSK 3925/4885CTSS 3911/4885CA1 3605/4885
US-20230242572-A1 a-CARBONYL ALKENYL ESTER PREPARATION METHOD THEREFOR AND APPLICATION THEREOF ACSL1, ACSL4, WEE1 CTSK 2595/4885CTSS 1913/4885CA1 1928/4885
US-12084444-B2 Spiro-lactam NMDA modulators and methods of using same GRIN1, GRIN2A, GRIN2C CTSK 4131/4885CTSS 4130/4885CA1 1579/4885
US-20250002495-A1 SPIRO-LACTAM NMDA MODULATORS AND METHODS OF USING SAME GRIN1, GRIN2A, GRIN2C CTSK 4131/4885CTSS 4130/4885CA1 1579/4885
US-12157736-B2 Spiro-lactam NMDA modulators and methods of using same GRIN1, GRIN2A, GRIN2C CTSK 4131/4885CTSS 4130/4885CA1 1579/4885
US-20260014146-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CDK2, CDK20, CDK1 CTSK 4394/4885CTSS 3999/4885CA1 2234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.