Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2444789 | 0.94 | MAPT (0.56) | ADRA1ASLC6A3CHRM2HTR1AADRA2A | |
| SCHEMBL2443821 | 0.88 | KEAP1 (0.54) | ADRA1ASLC6A3CHRM2ADRA2ADRD1 | |
| SCHEMBL2476877 | 0.87 | ADRA1A (0.50) | ADRA1ASLC6A3CHRM2HTR1AADRA2A | |
| SCHEMBL10817335 | 0.81 | KCNH2 (0.75) | ADRA1ASLC6A3CHRM2HTR1AADRA2A | |
| SCHEMBL11276352 | 0.80 | OPRM1 (0.61) | ADRA1ASLC6A3CHRM2HTR1AADRA2A | |
| Alverine SCHEMBL5059354 | 0.79 | KCNH2 (0.85) | ADRA1ASLC6A3CHRM2HTR1AADRA2A | |
| SCHEMBL27541878 | 0.79 | OPRK1 (0.56) | ADRA1ASLC6A3OPRM1HDAC1HDAC3 | |
| SCHEMBL2284795 | 0.78 | TDP1 (0.56) | ADRA1ASLC6A3CHRM2ADRA2ADRD1 | |
| Edetic Acid SCHEMBL1287423 | 0.78 | TSHR (0.56) | ADRA1ASLC6A3CHRM2ADRA2ADRD1 | |
| SCHEMBL2807141 | 0.78 | TDP1 (0.56) | ADRA1ASLC6A3CHRM2ADRA2ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910426-B1 | DIENE POLYMERISATION | INEOS SALES (UK) LTD (GB) | 2018-01-03 | — | — | EP | disclosed |
| US-8124698-B2 | Diene polymerisation | INEOS EUROPE LIMITED (GB) | 2012-02-28 | — | — | US | disclosed |
| EP-2371421-A1 | Ligands of insulin degrading enzyme and their uses | Université de Lille 2 Droit et Santé (FR) | 2011-10-05 | — | — | EP | disclosed |
| WO-2011107948-A2 | LIGANDS OF INSULIN DEGRADING ENZYME AND THEIR USES | UNIVERSITE LILLE 2 DROIT ET SANTE (FR) | 2011-09-09 | — | — | WO | disclosed |
| US-20100022724-A1 | Diene Polymerisation | INEOS SALES (UK) LIMITED (GB) | 2010-01-28 | — | — | US | disclosed |