Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2998396 | 0.85 | EPHX1 (0.44) | ALDH1A1SMN1; SMN2HPGDKMT2ANPSR1 | |
| SCHEMBL10587847 | 0.79 | ALDH1A1 (0.83) | ALDH1A1SMN1; SMN2HPGDKMT2ANPSR1 | |
| SCHEMBL11325844 | 0.78 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2MAPTGAAHDAC3 | |
| SCHEMBL29061111 | 0.76 | EPHX2 (0.50) | ALDH1A1SMN1; SMN2GAAHDAC3HDAC1 | |
| SCHEMBL24856036 | 0.76 | SMN1; SMN2 (0.62) | ALDH1A1SMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL28203533 | 0.75 | TSHR (0.38) | SMN1; SMN2EPHX1TSHR | |
| SCHEMBL5932290 | 0.75 | EPHX1 (0.43) | ALDH1A1SMN1; SMN2NPSR1EPHX1 | |
| SCHEMBL18909677 | 0.73 | SMN1; SMN2 (0.58) | ALDH1A1SMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL28819069 | 0.72 | NAAA (0.50) | EPHX1 | |
| SCHEMBL20650992 | 0.72 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2HPGDKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6657069-B2 | Reacting 6-aminocarbonylmethyl-4H-2,3- dioxin-4-one compound with alcohol or water to produce 3-oxopentanedicarboxylic acid amide esters; decyclization | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-12-02 | — | — | US | disclosed |
| US-20030130519-A1 | Amido compounds and process for producing the same | DAICEL CHEMICAL INDUSTRIES, LTD. | 2003-07-10 | — | — | US | disclosed |
| US-6548674-B2 | 6-aminocarbonylmethyl-4H-1,3-dioxin-4-ones made by reacting a 6-halomethyl-4H-1,3-dioxin-4-ones with primary or secondary amine and carbon monoxide; intermediate to 3-oxopentanedicarboxylic acid amides for drugs, polyamides | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-04-15 | — | — | US | disclosed |
| US-20010023297-A1 | Amido compounds and process for producing the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2001-09-20 | — | — | US | disclosed |
| EP-1132386-A1 | Amido compounds and process for producing the same | Daicel Chemical Industries, Ltd. (JP) | 2001-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130519-A1 | Amido compounds and process for producing the same | PAM, HAAO, DAO | ALDH1A1 664/4885SMN1; SMN2 3719/4885HPGD 320/4885 |
| US-20010023297-A1 | Amido compounds and process for producing the same | PAM, HAAO, DAO | ALDH1A1 664/4885SMN1; SMN2 3719/4885HPGD 320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.