Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.32 |
| ▸ | EDNRA | P25101 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7087252 | 0.88 | TP53 (0.36) | PPARGPPARAF10GPR119ABHD6 | |
| SCHEMBL7089977 | 0.85 | ALDH1A1 (0.38) | PPARGPPARAF10GPR119ABHD6 | |
| SCHEMBL7094641 | 0.81 | F10 (0.39) | F10 | |
| SCHEMBL7075244 | 0.80 | F10 (0.39) | F10LMNATSHRRAB9A | |
| SCHEMBL7087198 | 0.79 | RAB9A (0.42) | PPARGPPARADAOABHD6LMNA | |
| SCHEMBL7098737 | 0.78 | LMNA (0.40) | AGTR1EDNRALMNARAB9A | |
| SCHEMBL7072844 | 0.77 | LTB4R2 (0.40) | AGTR1EDNRALMNATSHRRAB9A | |
| SCHEMBL6752250 | 0.75 | MAPT (0.39) | F10AGTR1EDNRALMNA | |
| SCHEMBL6749855 | 0.73 | MAPT (0.37) | F10EDNRALMNATSHRRAB9A | |
| SCHEMBL7084908 | 0.72 | ABHD6 (0.39) | PPARGPPARADAOABHD6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030199698-A1 | Carbamic acid esters as inhibitors of factor xa | MERCK PATENT GMBH (DE) | 2003-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199698-A1 | Carbamic acid esters as inhibitors of factor xa | F11, F12, F13A1 | PPARG 2910/4885PPARA 2611/4885F10 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.