SCHEMBL7087250

SCHEMBL7087250

CCC(Cc1cccc(-c2noc(C)n2)c1)N(C(=O)O)c1ccc(-c2ccccc2S(=O)(=O)NC(C)(C)C)cc1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 1/20 0.38
USP30 Q70CQ3 5/20 0.37
EDNRB P24530 2/20 0.36
EDNRA P25101 2/20 0.36
ALOX5AP P20292 1/20 0.35
FEN1 P39748 1/20 0.35
CTSD P07339 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7087195 0.90 KMT2A (0.42) CTSDTP53
SCHEMBL7084905 0.83 DAO (0.39) CTSDTP53
SCHEMBL7084329 0.81 L3MBTL1 (0.43) CTSDTP53
SCHEMBL6752250 0.78 MAPT (0.39) MMP3EDNRBEDNRAALOX5APFEN1
SCHEMBL7072844 0.78 LTB4R2 (0.40) MMP3EDNRBEDNRA
SCHEMBL7096610 0.78 PDE4A (0.42) EDNRBEDNRAALOX5APFEN1TP53
SCHEMBL7087253 0.78 MMP3 (0.39) MMP3EDNRBEDNRAALOX5APFEN1
SCHEMBL7098737 0.76 LMNA (0.40) MMP3EDNRAALOX5APFEN1TP53
SCHEMBL6749825 0.76 HPGDS (0.41) ALOX5APFEN1CTSDTP53
SCHEMBL7087252 0.76 TP53 (0.36) EDNRATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030199698-A1 Carbamic acid esters as inhibitors of factor xa MERCK PATENT GMBH (DE) 2003-10-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199698-A1 Carbamic acid esters as inhibitors of factor xa F11, F12, F13A1 MMP3 934/4885USP30 2776/4885EDNRB 774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.