Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.63 |
| ▸ | DRD3 | P35462 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13113077 | 0.85 | DRD2 (0.66) | DRD2DRD3KDM4EALDH1A1GAA | |
| SCHEMBL3246963 | 0.84 | KDM4E (0.68) | DRD2DRD3KDM4EALDH1A1GAA | |
| SCHEMBL8870837 | 0.84 | KDM4E (0.67) | DRD2DRD3KDM4EALDH1A1GAA | |
| SCHEMBL13101463 | 0.83 | DRD2 (0.63) | DRD2DRD3KDM4EALDH1A1GAA | |
| SCHEMBL1204956 | 0.82 | KDM4E (0.69) | DRD2DRD3KDM4EALDH1A1GAA | |
| SCHEMBL6162398 | 0.82 | PYGL (0.69) | — | |
| SCHEMBL28918159 | 0.82 | ALOX15 (0.50) | DRD2DRD3KDM4EALDH1A1GAA | |
| SCHEMBL9397179 | 0.82 | DRD2 (0.74) | DRD2DRD3KDM4EALDH1A1GAA | |
| SCHEMBL7374142 | 0.82 | HDAC1 (0.72) | DRD2DRD3KDM4EALDH1A1HTR2C | |
| SCHEMBL7369673 | 0.82 | HDAC1 (0.72) | DRD2DRD3KDM4EALDH1A1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483367-B | Use of indole compounds in preparation of drugs | 上海柏晓企业管理咨询中心 | 2021-07-27 | — | — | CN | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |