Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | DRD2 | P14416 | 1/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.64 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7087439 | 0.84 | DRD2 (0.63) | KDM4EALDH1A1GAAMAPK1DRD2 | |
| SCHEMBL9397179 | 0.83 | DRD2 (0.74) | KDM4EALDH1A1GAAMAPK1DRD2 | |
| SCHEMBL7094858 | 0.82 | DRD2 (0.60) | KDM4EALDH1A1GAAMAPK1DRD2 | |
| SCHEMBL3262786 | 0.82 | HDAC3 (0.57) | KDM4EALDH1A1DRD3HSD17B10NPC1 | |
| SCHEMBL3253089 | 0.82 | PYGL (0.67) | — | |
| SCHEMBL16627604 | 0.82 | SMYD3 (0.51) | KDM4EALDH1A1GAAMAPK1DRD2 | |
| SCHEMBL29580477 | 0.81 | KDM4E (1.00) | KDM4EALDH1A1GAAMAPK1DRD2 | |
| SCHEMBL474835 | 0.81 | KDM4E (1.00) | KDM4EALDH1A1GAAMAPK1DRD2 | |
| SCHEMBL13113077 | 0.81 | DRD2 (0.66) | KDM4EALDH1A1GAAMAPK1DRD2 | |
| SCHEMBL13753861 | 0.81 | DRD2 (0.84) | KDM4EALDH1A1GAAMAPK1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651639-B1 | BENZOFURAN DERIVATIVES AND THEIR USE IN THE TREATMENT OF MICROBIAL INFECTIONS | ARPIDA AG (CH) | 2010-05-26 | — | — | EP | disclosed |
| US-7524854-B2 | Benzofuran derivatives and their use in the treatment of microbial infections | ARPIDA AG (CH) | 2009-04-28 | — | — | US | disclosed |
| US-20060154943-A1 | Benzofuran derivatives and their use in the treatment of microbial infections | ARPIDA AG (CH) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154943-A1 | Benzofuran derivatives and their use in the treatment of microbial infections | DCXR, NLRP3, NISCH | KDM4E 1957/4885ALDH1A1 891/4885GAA 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.