SCHEMBL7087726

SCHEMBL7087726

C=CC(=O)OC(c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 2/20 0.39
KCNN4 O15554 3/20 0.38
RORC P51449 7/20 0.38
NR1I2 O75469 2/20 0.38
CYP1A1 P04798 2/20 0.36
CYP1B1 Q16678 2/20 0.36
MAPT P10636 2/20 0.35
LMNA P02545 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HSD11B1 P28845 1/20 0.34
MAOB P27338 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
XBP1 P17861 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12975900 0.93 TGM2 (0.40) TGM2RORCNR1I2MAPTLMNA
SCHEMBL7939162 0.85 LMNA (0.41) TGM2KCNN4MAPTLMNANPSR1
SCHEMBL13138858 0.84 TGM2 (0.34) TGM2MAPTLMNANPSR1
SCHEMBL9418936 0.78 RORC (0.39) KCNN4RORCNR1I2CYP1A1CYP1B1
SCHEMBL14827328 0.78 SMN1; SMN2 (0.40) TGM2KCNN4CYP1A1CYP1B1MAPT
SCHEMBL7084775 0.75 RORC (0.38) KCNN4RORCNR1I2MAPTLMNA
SCHEMBL10880826 0.75 RORC (0.32) RORC
SCHEMBL8736667 0.74
SCHEMBL6862502 0.71 LMNA (0.38) TGM2RORCCYP1A1CYP1B1MAPT
SCHEMBL6862507 0.71 ALDH1A1 (0.38) TGM2RORCCYP1A1CYP1B1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030027884-A1 Binder composition for photocatalytic coating and photocatalytic coating film manufactured using the same SAMHWA PAINTS INDUSTRIES CO., LTD. (KR) 2003-02-06 US disclosed