SCHEMBL7939162

SCHEMBL7939162

C=CC(=O)OC(c1ccccc1)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
MAPT P10636 3/20 0.41
NPSR1 Q6W5P4 3/20 0.41
THRB P10828 1/20 0.39
ALDH1A1 P00352 3/20 0.39
TSHR P16473 2/20 0.39
AKT1 P31749 1/20 0.37
HTT P42858 1/20 0.37
PTPN1 P18031 1/20 0.36
MAOB P27338 1/20 0.36
S1PR4 O95977 1/20 0.35
S1PR1 P21453 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.34
TGM2 P21980 2/20 0.34
KCNN4 O15554 1/20 0.34
CYP2C19 P33261 1/20 0.34
HIF1A Q16665 1/20 0.34
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12975900 0.91 TGM2 (0.40) LMNAMAPTNPSR1THRBALDH1A1
SCHEMBL7087726 0.85 TGM2 (0.39) LMNAMAPTNPSR1HTTMAOB
SCHEMBL4606750 0.82 THRB (0.41) LMNAMAPTNPSR1THRBALDH1A1
SCHEMBL13138858 0.82 TGM2 (0.34) LMNAMAPTNPSR1THRBTGM2
SCHEMBL20102170 0.81 CYP2C19 (0.41) LMNAMAPTNPSR1THRBALDH1A1
SCHEMBL7939165 0.80 THRB (0.37) LMNAMAPTNPSR1THRBALDH1A1
SCHEMBL7859075 0.80 HTT (0.46) MAPTNPSR1THRBALDH1A1TSHR
SCHEMBL22472203 0.78 THRB (0.43) MAPTNPSR1THRBALDH1A1TSHR
SCHEMBL438661 0.78 THRB (0.43) MAPTNPSR1THRBALDH1A1TSHR
SCHEMBL10880826 0.77 RORC (0.32) NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111542348-B Material for intraocular lens 株式会社目立康 2022-07-05 CN claimed
CN-113543753-B Method for absorbing or discharging moisture in ophthalmic medical device and ophthalmic medical device 国立大学法人东北大学 2024-04-19 CN disclosed
CN-113543753-A Method for absorbing or discharging moisture in ophthalmic medical device, and ophthalmic medical device 国立大学法人东北大学 2021-10-22 CN disclosed
US-10739678-B2 Photocurable composition, pattern forming method, and method for manufacturing device FUJIFILM CORPORATION (JP) 2020-08-11 US disclosed
US-10641938-B2 Film forming composition, hardcoat film, polarizing plate, and method for manufacturing hydrophilized hardcoat film FUJIFILM CORPORATION (JP) 2020-05-05 US disclosed
US-20180120698-A1 PHOTOCURABLE COMPOSITION, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING DEVICE FUJIFILM CORPORATION (JP) 2018-05-03 US disclosed
US-6277940-B1 TRANSPARENCY AND FLEXIBILITY, REFRACTIVE INDEX, CAN BE INSERTED FROM A SMALL INCISION MENICON CO. LTD (JP) 2001-08-21 US disclosed
EP-0443370-B1 Dental materials BAYER AG (DE) 1994-08-24 EP disclosed
EP-0373385-B1 USE OF ESTERS OF (METH-)ACRYLATES CONTAINING PERFLUOR ALKYL GROUPS IN DENTISTRY Th. Goldschmidt AG (DE) 1993-01-13 EP disclosed
EP-0373384-B1 ESTER OF (METH-)ACRYLIC ACID CONTAINING PERFLUOR ALKYL GROUPS, THEIR PREPARATION AND USE IN DENTISTRY Th. Goldschmidt AG (DE) 1992-10-28 EP disclosed
EP-0443370-A2 Dental materials BAYER AG (DE) 1991-08-28 EP disclosed
US-5026902-A Low solubility, higher mechanical strength, curable, good adhesion Th. Goldschmidt AG & GDF Gesellschaft fur Dentale Forschung u. Innovationen GmbH (DE) 1991-06-25 US disclosed
EP-0373384-A1 Ester of (meth-)acrylic acid containing perfluor alkyl groups, their preparation and use in dentistry Th. Goldschmidt AG (DE) 1990-06-20 EP disclosed
EP-0201031-B1 (METH)ACRYLIC ESTERS AND THEIR USE BAYER AG (DE) 1989-08-02 EP disclosed
EP-0201778-B1 (METH)-ACRYLIC-ACID ESTERS AND THEIR USE BAYER AG (DE) 1988-12-28 EP disclosed
US-4752338-A (Meth)-acrylic acid esters BAYER AKTIENGESELLSCHAFT (DE) 1988-06-21 US disclosed
US-4665217-A DENTAL FILLERS AND COATINGS BAYER AKTIENGESELLSCHAFT (DE) 1987-05-12 US disclosed
EP-0201778-A1 (Meth)-acrylic-acid esters and their use BAYER AG (DE) 1986-11-20 EP disclosed
EP-0201031-A2 (Meth)acrylic esters and their use BAYER AG (DE) 1986-11-12 EP disclosed
US-4356296-A Fluorinated diacrylic esters and polymers therefrom THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1982-10-26 US disclosed