Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442976 | 0.85 | SCN9A (0.62) | CYP3A4CYP2D6CYP2C9SCN9AMAP3K14 | |
| SCHEMBL6664214 | 0.84 | ATP4A (0.60) | CYP3A4CYP2D6CYP2C9SCN9AMAP3K14 | |
| SCHEMBL6660829 | 0.84 | ATP4A (0.60) | TSHRRECQLCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7436637 | 0.84 | KDM4E (0.63) | CYP3A4CYP2D6CYP2C9SCN9AHDAC1 | |
| SCHEMBL7436415 | 0.84 | MAPT (0.63) | CYP3A4CYP2D6CYP2C9SCN9AHDAC3 | |
| SCHEMBL22352575 | 0.83 | TSHR (0.57) | TSHRRECQLCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL168593 | 0.82 | ALDH1A1 (0.56) | RECQLCYP3A4CYP2D6CYP2C9SCN9A | |
| Hydrochloric Acid SCHEMBL30882415 | 0.81 | MAPT (0.56) | RECQLCYP3A4CYP2D6CYP2C9SCN9A | |
| SCHEMBL7434052 | 0.80 | CYP3A4 (0.52) | TSHRRECQLCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7440522 | 0.80 | CYP3A4 (0.61) | CYP3A4CYP2D6CYP2C9SCN9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144308-A1 | Fructose 1,6-bisphosphatase inhibitors | BAUER PAUL H (US) | 2003-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144308-A1 | Fructose 1,6-bisphosphatase inhibitors | FBP1, HK1, G6PC1 | TSHR 4244/4885RECQL 642/4885CYP3A4 546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.