Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7090243 | 0.87 | MMP1 (0.44) | PGRKAT6AACLYCCKBRITGAV | |
| SCHEMBL7084134 | 0.83 | KAT6A (0.44) | PGRKAT6ADPP4DPP7ACLY | |
| SCHEMBL7087005 | 0.79 | ALDH1A1 (0.45) | USP2CYP1A2CYP3A4HIF1ACYP2D6 | |
| SCHEMBL6994772 | 0.74 | USP2 (0.53) | PGRKAT6AACLYCCKBRUSP2 | |
| SCHEMBL6990928 | 0.73 | USP2 (0.55) | PGRKAT6AACLYCCKBRUSP2 | |
| SCHEMBL16108775 | 0.72 | PARG (0.59) | PGRKAT6AACLYBRD4RXFP1 | |
| SCHEMBL7077236 | 0.71 | MMP1 (0.52) | PGRKAT6AACLYUSP2CYP1A2 | |
| SCHEMBL30367627 | 0.71 | PGR (0.46) | PGRKAT6AACLYBRD4RXFP1 | |
| SCHEMBL7078089 | 0.70 | USP2 (0.44) | PGRKAT6AACLYCCKBRUSP2 | |
| SCHEMBL27589461 | 0.70 | CYP3A4 (0.48) | PGRKAT6ADPP4DPP7CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303482-A2 | N-SUBSTITUTED-1-AMINO-1,1-DIALKYLCARBOXYLIC ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002008177-A2 | N-SUBSTITUTED-1-AMINO-1,1-DIALKYLCARBOXYLIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-01-31 | — | — | WO | disclosed |