SCHEMBL708991

SCHEMBL708991

CCCC(CCC)NC(=O)c1ccc2c(c1)OCCO2

nearest known ligand 0.80

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.80
TAS1R3 Q7RTX0 13/20 0.76
TAS1R1 Q7RTX1 13/20 0.76
HPGD P15428 1/20 0.57
ATM Q13315 1/20 0.56
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
KDM4E B2RXH2 1/20 0.55
MAPK1 P28482 1/20 0.55
TP53 P04637 1/20 0.54
GLA P06280 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29412435 1.00 SMN1; SMN2 (0.80) SMN1; SMN2TAS1R3TAS1R1HPGDATM
SCHEMBL701771 0.95 TAS1R3 (0.73) SMN1; SMN2TAS1R3TAS1R1HPGDNPC1
SCHEMBL701035 0.92 TAS1R3 (0.90) SMN1; SMN2TAS1R3TAS1R1HPGD
SCHEMBL17822213 0.89 SMN1; SMN2 (1.00) SMN1; SMN2TAS1R3TAS1R1HPGDATM
SCHEMBL20404308 0.87 TAS1R3 (0.95) SMN1; SMN2TAS1R3TAS1R1HPGD
SCHEMBL701951 0.86 TAS1R3 (1.00) SMN1; SMN2TAS1R3TAS1R1HPGD
SCHEMBL702767 0.85 TAS1R3 (1.00) SMN1; SMN2TAS1R3TAS1R1NPC1RAB9A
SCHEMBL709734 0.85 TAS1R3 (0.83) SMN1; SMN2TAS1R3TAS1R1HPGD
SCHEMBL11902564 0.85 TAS1R3 (0.76) SMN1; SMN2TAS1R3TAS1R1
SCHEMBL20860871 0.84 TAS1R3 (0.76) SMN1; SMN2TAS1R3TAS1R1HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11268952-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof FIRMENICH INCORPORATED (US) 2022-03-08 US disclosed
US-20200225217-A1 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF FIRMENICH INCORPORATED (US) 2020-07-16 US disclosed
US-10557845-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof FIRMENICH INCORPORATED (US) 2020-02-11 US disclosed
EP-1659881-B1 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF SENOMYX INC (US) 2019-04-03 EP disclosed
EP-3431464-A2 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF Senomyx Inc. (US) 2019-01-23 EP disclosed
EP-3235811-A1 PROCESS OF PREPARING OXALAMIDES Senomyx, Inc. (US) 2017-10-25 EP disclosed
EP-2010009-B1 PROCESSES FOR PREPARING SOLID FLAVORANT COMPOSITIONS SENOMYX INC (US) 2017-06-14 EP disclosed
EP-2010009-B1 PROCESSES FOR PREPARING SOLID FLAVORANT COMPOSITIONS SENOMYX INC (US) 2017-06-14 EP disclosed
US-9072313-B2 Comestible compositions comprising high potency savory flavorants, and processes for producing them SENOMYX, INC. (US) 2015-07-07 US disclosed
US-9072313-B2 Comestible compositions comprising high potency savory flavorants, and processes for producing them SENOMYX, INC. (US) 2015-07-07 US disclosed
US-8124121-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof SENOMYX, INC. (US) 2012-02-28 US disclosed
US-8124121-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof SENOMYX, INC. (US) 2012-02-28 US disclosed
US-8124121-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof SENOMYX, INC. (US) 2012-02-28 US disclosed
US-20090280230-A1 COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM SENOMYX, INC. 2009-11-12 US disclosed
US-20090280230-A1 COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM SENOMYX, INC. 2009-11-12 US disclosed
US-20090111834-A1 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF SENOMYX, INC. 2009-04-30 US disclosed
US-20090111834-A1 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF SENOMYX, INC. 2009-04-30 US disclosed
US-7476399-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof SENOMYX INC. (US) 2009-01-13 US disclosed
US-7476399-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof SENOMYX INC. (US) 2009-01-13 US disclosed
WO-2007124152-A2 COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM SENOMYX, INC. (US) 2007-11-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200225217-A1 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF TAS1R2, TAS1R1, TAS2R40 SMN1; SMN2 2568/4885TAS1R3 5/4885TAS1R1 2/4885
US-10557845-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof TAS1R2, TAS1R1, TAS2R40 SMN1; SMN2 2606/4885TAS1R3 5/4885TAS1R1 2/4885
US-20090280230-A1 COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM TAS1R1, TAS1R2, GRM1 SMN1; SMN2 1180/4885TAS1R3 12/4885TAS1R1 1/4885
US-20090111834-A1 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF TAS1R2, TAS1R1, TAS2R30 SMN1; SMN2 2560/4885TAS1R3 5/4885TAS1R1 2/4885
US-11268952-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof TAS2R40, TAS1R2, TAS1R1 SMN1; SMN2 2642/4885TAS1R3 5/4885TAS1R1 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.