Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.41 |
| ▸ | REN | P00797 | 4/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PEPD | P12955 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7087507 | 0.81 | ACE (0.48) | ACERENLTA4HKDM4EF2 | |
| SCHEMBL7092404 | 0.80 | ACE (0.50) | ACERENLTA4HKDM4EF2 | |
| SCHEMBL7090676 | 0.75 | ACE (0.56) | ACERENLTA4HKDM4EF2 | |
| SCHEMBL5509931 | 0.75 | ARG1 (0.47) | ALOX15 | |
| SCHEMBL9436829 | 0.75 | ARG1 (0.47) | ALOX15 | |
| SCHEMBL3911823 | 0.74 | ACE (0.49) | ACERENLTA4HKDM4EF2 | |
| SCHEMBL7090630 | 0.74 | ACE (0.46) | ACERENLTA4HKDM4EF2 | |
| Hydrochloric Acid SCHEMBL8932134 | 0.74 | ARG1 (0.46) | ALOX15 | |
| SCHEMBL7087534 | 0.74 | ACE (0.55) | ACELTA4H | |
| SCHEMBL7977238 | 0.72 | NOS2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003075901-A2 | USE OF S-SUBSTITUTED L-CRYSTEINE FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF DERMATOLOGICAL DISORDERS | GHISALBERTI CARLO (BR) | 2003-09-18 | — | — | WO | disclosed |