Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 3/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509931 | 0.87 | ARG1 (0.47) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL9436829 | 0.87 | ARG1 (0.47) | NOS2NOS1NOS3ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL8932134 | 0.86 | ARG1 (0.46) | NOS2NOS1NOS3ARG1ARG2 | |
| SCHEMBL537841 | 0.76 | BHMT (0.50) | NOS2NOS1NOS3 | |
| SCHEMBL537840 | 0.76 | BHMT (0.50) | NOS2NOS1NOS3 | |
| SCHEMBL6655681 | 0.76 | BHMT (0.50) | NOS2NOS1NOS3 | |
| SCHEMBL6130709 | 0.73 | DPP7 (0.34) | NOS2NOS1NOS3ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL7976942 | 0.73 | SLC1A3 (0.38) | — | |
| Phosphonic Acid SCHEMBL27587576 | 0.73 | BHMT (0.49) | NOS2NOS1NOS3 | |
| SCHEMBL7090164 | 0.72 | ACE (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001005748-A1 | OLIGOMERIC AMINO ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | MONSANTO COMPANY (US) | 2001-01-25 | — | — | WO | disclosed |