Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2937196 | 0.76 | CAMK2D (0.49) | NR4A2EGFRERBB2IGF1RPDGFRB | |
| SCHEMBL5429556 | 0.67 | GPR84 (0.62) | NR4A2EGFRHTR1AHTR7HTR6 | |
| SCHEMBL7737770 | 0.67 | PDGFRB (0.44) | NR4A2EGFRERBB2IGF1RPDGFRB | |
| SCHEMBL5879252 | 0.67 | PDGFRB (0.50) | NR4A2EGFRERBB2IGF1RPDGFRB | |
| SCHEMBL7826604 | 0.65 | KDR (0.68) | EGFRERBB2IGF1RPDGFRBKIT | |
| SCHEMBL20624158 | 0.65 | SIRT2 (0.63) | NR4A2EGFRERBB2IGF1RPDGFRB | |
| SCHEMBL14215759 | 0.64 | HTR1A (0.55) | NR4A2EGFRCAMK2DHTR1AHTR7 | |
| SCHEMBL1558405 | 0.64 | NR4A2 (0.61) | NR4A2GABRA1GABRB1GABRA3GABRB2 | |
| SCHEMBL27795085 | 0.64 | GABRA1 (0.64) | NR4A2GABRA1GABRB1GABRA3GABRB2 | |
| SCHEMBL28514484 | 0.64 | PTPN1 (0.55) | EGFRERBB2IGF1RPDGFRBKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1283836-A2 | NEUROPROTECTIVE AND ANTI-PROLIFERATIVE COMPOUNDS | Aegera Therapeutics Inc. (CA) | 2003-02-19 | — | — | EP | disclosed |
| WO-2001087887-A2 | NEUROPROTECTIVE AND ANTI-PROLIFERATIVE COMPOUNDS | AEGERA THERAPEUTICS INC. (CA) | 2001-11-22 | — | — | WO | disclosed |