SCHEMBL7090928

SCHEMBL7090928

NC(=O)c1csc(-c2cccc(N)c2)n1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.56
SCN9A Q15858 1/20 0.56
HTR2B P41595 1/20 0.54
ACHE P22303 1/20 0.52
ALDH1A1 P00352 4/20 0.49
HDAC1 Q13547 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
CYP2C19 P33261 1/20 0.46
TLR7 Q9NYK1 3/20 0.45
TDP1 Q9NUW8 1/20 0.44
HPGDS O60760 2/20 0.44
TSHR P16473 1/20 0.44
RECQL P46063 1/20 0.44
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 2/20 0.44
MAPT P10636 2/20 0.44
KMT2A Q03164 2/20 0.44
LMNA P02545 1/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6182649 0.88 HPGDS (0.57) ACHEALDH1A1HDAC1HDAC8HDAC6
SCHEMBL14564378 0.85 CYP2C9 (0.62) CYP2C9SCN9AHTR2BACHEALDH1A1
SCHEMBL1786612 0.85 HSD17B1 (0.60) CYP2C9SCN9AHTR2BACHEALDH1A1
SCHEMBL31351001 0.84 TLR7 (0.62) CYP2C9SCN9AHTR2BACHEALDH1A1
Hydrochloric Acid SCHEMBL27746131 0.82 TLR7 (0.60) CYP2C9SCN9AHTR2BACHEALDH1A1
SCHEMBL168519 0.82 HTR2B (0.66) CYP2C9SCN9AHTR2BACHEALDH1A1
SCHEMBL7089339 0.79 GAA (0.51) CYP2C9SCN9AHTR2BACHEALDH1A1
SCHEMBL31350850 0.79 MKNK1 (0.53) CYP2C9SCN9AHTR2BACHEALDH1A1
SCHEMBL1812154 0.76 HDAC6 (0.70) CYP2C9ALDH1A1HDAC6CYP2C19TLR7
SCHEMBL31350948 0.76 HDAC6 (0.70) CYP2C9ALDH1A1HDAC6CYP2C19TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025003987-A1 NOVEL CARBOXAMIDE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 동화약품주식회사 2025-01-02 WO disclosed
US-20030144308-A1 Fructose 1,6-bisphosphatase inhibitors BAUER PAUL H (US) 2003-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030144308-A1 Fructose 1,6-bisphosphatase inhibitors FBP1, HK1, G6PC1 CYP2C9 598/4885SCN9A 4193/4885HTR2B 2954/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.