Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7090971 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1MAPTRAB9AMAPK1 | |
| SCHEMBL1342675 | 0.76 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1MAPTRAB9AMAPK1 | |
| SCHEMBL10177473 | 0.76 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1MAPTRAB9AMAPK1 | |
| SCHEMBL1342671 | 0.76 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1MAPTRAB9AMAPK1 | |
| SCHEMBL2037488 | 0.71 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1MAPTRAB9AMAPK1 | |
| SCHEMBL21872319 | 0.71 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1MAPTRAB9AMAPK1 | |
| SCHEMBL2037491 | 0.71 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1MAPTRAB9AMAPK1 | |
| SCHEMBL4900509 | 0.71 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1MAPTRAB9AMAPK1 | |
| SCHEMBL10741171 | 0.70 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1MAPTRAB9AMAPK1 | |
| SCHEMBL17412695 | 0.70 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1MAPTRAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176477-A1 | Isothiazolecarboxylic acid derivatives and their use as microbicides | NIHON BAYER AGROCHEM, K.K. (JP) | 2003-09-18 | — | — | US | disclosed |
| EP-1261592-A1 | ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2002-12-04 | — | — | EP | disclosed |
| WO-2001055124-A1 | ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176477-A1 | Isothiazolecarboxylic acid derivatives and their use as microbicides | IFNG, MPO, CD14 | SMN1; SMN2 4824/4885ALDH1A1 430/4885MAPT 4555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.