Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 6/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7091215 | 1.00 | RAB9A (0.49) | RAB9AHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL15285027 | 0.74 | HPGD (0.60) | RAB9AHPGDALDH1A1KDM4EPKM | |
| SCHEMBL7090110 | 0.74 | NPC1 (0.46) | RAB9AHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL7090105 | 0.74 | NPC1 (0.46) | RAB9AHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL7093379 | 0.73 | NPSR1 (0.43) | RAB9AHPGDALDH1A1KDM4EMEN1 | |
| SCHEMBL7093380 | 0.73 | NPSR1 (0.43) | RAB9AHPGDALDH1A1KDM4EMEN1 | |
| SCHEMBL7663081 | 0.72 | RAB9A (0.52) | RAB9AHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL7092976 | 0.70 | ALDH1A1 (0.42) | RAB9AHPGDALDH1A1LMNAMEN1 | |
| SCHEMBL7092979 | 0.70 | ALDH1A1 (0.42) | RAB9AHPGDALDH1A1LMNAMEN1 | |
| SCHEMBL7663073 | 0.69 | HPGD (0.52) | RAB9AHPGDALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | claimed |
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | disclosed |