Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7092979 | 1.00 | ALDH1A1 (0.42) | ALDH1A1NPSR1SMN1; SMN2HTTRAB9A | |
| SCHEMBL7093379 | 0.83 | NPSR1 (0.43) | ALDH1A1NPSR1SMN1; SMN2HTTRAB9A | |
| SCHEMBL7093380 | 0.83 | NPSR1 (0.43) | ALDH1A1NPSR1SMN1; SMN2HTTRAB9A | |
| SCHEMBL7090105 | 0.81 | NPC1 (0.46) | ALDH1A1NPSR1SMN1; SMN2HTTRAB9A | |
| SCHEMBL7090110 | 0.81 | NPC1 (0.46) | ALDH1A1NPSR1SMN1; SMN2HTTRAB9A | |
| SCHEMBL7091213 | 0.70 | RAB9A (0.49) | ALDH1A1SMN1; SMN2HTTRAB9AHPGD | |
| SCHEMBL28910418 | 0.70 | NPSR1 (0.50) | ALDH1A1NPSR1SMN1; SMN2HTTRAB9A | |
| SCHEMBL6031703 | 0.68 | TRPM8 (0.48) | ALDH1A1NPSR1HTTRAB9AHPGD | |
| SCHEMBL9446234 | 0.68 | TRPM8 (0.48) | ALDH1A1NPSR1HTTRAB9AHPGD | |
| SCHEMBL9446229 | 0.68 | TRPM8 (0.48) | ALDH1A1NPSR1HTTRAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | claimed |
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | disclosed |